CymitQuimica logo

CAS 3868-34-6

:

8-Hydrazinyladenosine

Description:
8-Hydrazinyladenosine is a modified nucleoside that features a hydrazine functional group attached to the adenine base at the 8-position. This compound is characterized by its structural similarity to adenosine, which is a key component of nucleic acids and plays a crucial role in cellular energy transfer and signaling. The presence of the hydrazine group imparts unique reactivity, making it of interest in various biochemical applications, including potential roles in drug development and as a biochemical probe. 8-Hydrazinyladenosine can participate in redox reactions and may exhibit different biological activities compared to its unmodified counterpart. Its solubility and stability in biological systems can vary, influencing its bioavailability and interaction with enzymes or receptors. Additionally, the compound's ability to form hydrogen bonds and participate in stacking interactions can affect its binding affinity to nucleic acid structures. Overall, 8-Hydrazinyladenosine represents a valuable tool in the study of nucleoside chemistry and its applications in medicinal chemistry.
Formula:C10H15N7O4
InChI:InChI=1S/C10H15N7O4/c11-7-4-8(14-2-13-7)17(10(15-4)16-12)9-6(20)5(19)3(1-18)21-9/h2-3,5-6,9,18-20H,1,12H2,(H,15,16)(H2,11,13,14)/t3-,5-,6-,9-/m1/s1
InChI key:InChIKey=XMRQUQWRGIIBTK-UUOKFMHZSA-N
SMILES:N(N)=C1N(C=2C(N1)=C(N)N=CN2)[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O
Synonyms:
  • 8-Hydrazinyladenosine
  • NSC 197216
  • Adenosine, 8-hydrazinyl-
  • NSC 95945
  • Adenosine, 8-hydrazino-
  • See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 2 products.
  • 8-Hydrazinoadenosine
    Targetmol
    + Info

    8-Hydrazinoadenosine

    CAS:
    8-Hydrazinoadenosine is a Nucleoside Derivative - 8-Modified purine nucleoside.
    Formula:C10H15N7O4
    Color and Shape:Solid
    Molecular weight:297.27

    Ref: TM-TNU0287

  • 8-Hydrazinoadenosine
    Biosynth
    + Info

    8-Hydrazinoadenosine

    CAS:
    <p>8-Hydrazinoadenosine is an inhibitor of phosphodiesterase, which is a key enzyme in the regulation of cellular processes. 8-Hydrazinoadenosine binds to the active site of the enzyme and inhibits its function. This binding prevents hydrolysis of the phosphate bond between two nucleotides and so prevents the formation of a new nucleotide from a nucleoside and a phosphate molecule. 8-Hydrazinoadenosine has been shown to inhibit phosphodiesterases in vitro and in animals, including rat brain and mouse lung. Strategies for 8-hydrazinoadenosine commercialization have been investigated, including attaching it to other molecules that are more easily absorbed by cells or using irradiation to produce 8-aminoadenosine, which can be converted into 8-hydrazinoadenosine.</p>
    Purity:Min. 95%

    Ref: 3D-FH162950

    ne
    To inquire