CAS 3868-36-8

8-Benzyloxyguanosine

Description:

8-Benzyloxyguanosine is a modified nucleoside that features a guanine base linked to a ribose sugar, with a benzyl ether substituent at the 8-position of the guanine moiety. This compound is characterized by its unique structural modifications, which enhance its solubility and stability compared to unmodified nucleosides. It typically exhibits properties such as being a white to off-white crystalline solid, with a moderate melting point and solubility in polar organic solvents. The presence of the benzyl group can influence its biological activity, potentially affecting interactions with nucleic acid structures and enzymes. 8-Benzyloxyguanosine is often utilized in biochemical research, particularly in studies involving nucleic acid synthesis, signaling pathways, and as a potential therapeutic agent due to its ability to mimic natural nucleosides. Its CAS number, 3868-36-8, is a unique identifier that facilitates the cataloging and identification of this compound in chemical databases and literature.

Formula: C₁₇H₁₉N₅O₆

InChI: InChI=1/C17H19N5O6/c18-16-20-13-10(14(26)21-16)19-17(27-7-8-4-2-1-3-5-8)22(13)15-12(25)11(24)9(6-23)28-15/h1-5,9,11-12,15,23-25H,6-7H2,(H3,18,20,21,26)/t9-,11-,12-,15-/m1/s1

SMILES: c1ccc(cc1)COc1nc2c([nH]c(=N)nc2O)n1[C@H]1[C@@H]([C@@H]([C@@H](CO)O1)O)O

Synonyms:

• 2-Amino-8-(benzyloxy)-9-pentofuranosyl-1,9-dihydro-6H-purin-6-one
• 6H-purin-6-one, 2-amino-1,9-dihydro-9-pentofuranosyl-8-(phenylmethoxy)-
• 2-amino-8-(benzyloxy)-9-pentofuranosyl-3,9-dihydro-6H-purin-6-one
• 8-BENZYLOXYGUANOSINE
• NSC 90391
• 8-(PhenylMethoxy)guanosine
• 2-Amino-8-(benzyloxy)-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one

8-(Benzyloxy)guanosine

CAS: 3868-36-8

Ref: 7W-GC4001

8-Benzyloxyguanosine

CAS: 3868-36-8

8-Benzyloxyguanosine is a Nucleoside Derivative - 8-Modified purine nucleoside.

Formula: C₁₇H₁₉N₅O₆

Color and Shape: Solid

Molecular weight: 389.36

Ref: TM-TNU0930

8-(Benzyloxy)guanosine

CAS: 3868-36-8

8-(Benzyloxy)guanosine is a novel nucleoside analog that is an activator of ribonucleotide reductase. It has been shown to inhibit the proliferation of cancer cells in vitro and in vivo, as well as inhibit the production of diphosphate from ATP. This compound also has antiviral activity against herpes simplex virus type 1 (HSV-1) and human immunodeficiency virus type 1 (HIV-1). 8-(Benzyloxy)guanosine is synthesized by reacting the 8-hydroxy group on guanosine with benzaldehyde, followed by phosphorylation with diphosphate. This compound has CAS No. 3868-36-8 and can be used for research purposes only.

Formula: C₁₇H₁₉N₅O₆

Purity: Min. 95 Area-%

Color and Shape: White To Off-White Solid

Molecular weight: 389.36 g/mol

Ref: 3D-MB16633

8-(Benzyloxy)guanosine

Controlled Product

CAS: 3868-36-8

Applications Guanosine (G) derivative.

Formula: C₁₇H₁₉N₅O₆

Color and Shape: Neat

Molecular weight: 389.36

Ref: TR-B286780