Description:4-Fluoroindole is a chemical compound characterized by the presence of a fluorine atom at the 4-position of the indole ring system. Indole itself is a bicyclic structure composed of a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring. The introduction of the fluorine atom can influence the compound's electronic properties, reactivity, and biological activity. 4-Fluoroindole is typically a white to off-white solid and is soluble in organic solvents. It is of interest in medicinal chemistry and materials science due to its potential applications in pharmaceuticals, particularly as a building block for the synthesis of various bioactive compounds. The presence of the fluorine atom can enhance lipophilicity and metabolic stability, making it a valuable modification in drug design. Additionally, 4-fluoroindole can participate in various chemical reactions, including electrophilic substitutions and coupling reactions, which are useful in synthetic organic chemistry. Safety data should be consulted for handling and storage, as with any chemical substance.
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