CAS 38753-77-4: 7α-(Thiomethyl)spironolactone

Formula: C₂₃H₃₂O₃S

InChI: InChI=1S/C23H32O3S/c1-21-8-4-15(24)12-14(21)13-18(27-3)20-16(21)5-9-22(2)17(20)6-10-23(22)11-7-19(25)26-23/h12,16-18,20H,4-11,13H2,1-3H3/t16-,17-,18+,20+,21-,22-,23+/m0/s1

InChI key: InChIKey=FWRDLPQBEOKIRE-RJKHXGPOSA-N

SMILES: O=C1OC2(CC1)CCC3C4C(SC)CC5=CC(=O)CCC5(C)C4CCC32C

Synonyms:

• Pregn-4-ene-21-carboxylic acid, 17-hydroxy-7-(methylthio)-3-oxo-, γ-lactone, (7α,17α)-
• Spiro[17H-cyclopenta[a]phenanthrene-17,2′(5′H)-furan], pregn-4-ene-21-carboxylic acid deriv.
• SC 26519
• 3-(3-Oxo-7α-methylthio-17β-hydroxy-4-androsten-17α-yl)propionic acid γ-lactone
• 7α-(Methylthio)spironolactone

7-α-Thiomethyl Spironolactone

CAS: 38753-77-4

• Formula: C₂₃H₃₂O₃S
• Color and Shape: White To Off-White Solid
• Molecular weight: 388.57

7α-Thiomethylspironolactone

CAS: 38753-77-4

7α-Thiomethylspironolactone is a major metabolite of the synthetic steroid spironolactone.1,2

• Formula: C₂₃H₃₂O₃S
• Color and Shape: Liquid
• Molecular weight: 388.56

7-α-Thiomethyl Spironolactone-13C-d3

CAS: 38753-77-4

• Formula: C₂₂₁₃CH₂₉D₃O₃S
• Molecular weight: 392.58

7alpha-Thiomethyl Spironolactone

CAS: 38753-77-4

Applications A metabolite of Spironolactone. References Gochman, N., et al.: J. Pharmacol. Exp. Ther., 135, …

• Formula: C₂₃H₃₂O₃S
• Color and Shape: Neat
• Molecular weight: 388.56

7Alpha-Thiomethyl Spironolactone-d7 (Major)

CAS: 38753-77-4

Applications A labelled metabolite of Spironolactone. References Gochman, N., et al.: J. Pharmacol. Exp. Ther., …

• Formula: C₂₃H₂₅D₇O₃S
• Color and Shape: Neat
• Molecular weight: 395.61

7a-Thiomethyl spironolactone

CAS: 38753-77-4

Spironolactone is an antihypertensive drug that acts as a mineralocorticoid receptor antagonist, competitively binding to …

• Formula: C₂₃H₃₂O₃S
• Purity: Min. 95%
• Molecular weight: 388.56 g/mol