CAS 387867-14-3

1-Piperazinecarboxamide,4-[6-methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinyl]-N-[4-(1-methylethoxy)phenyl]-, sulfate (1:1)

Description:

1-Piperazinecarboxamide, 4-[6-methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinyl]-N-[4-(1-methylethoxy)phenyl]-, sulfate (1:1), identified by CAS number 387867-14-3, is a complex organic compound characterized by its multi-functional structure. It features a piperazine moiety, which is known for its role in various pharmacological activities, and a quinazoline core that contributes to its potential biological activity. The presence of methoxy and piperidinyl groups enhances its lipophilicity and may influence its interaction with biological targets. This compound is typically synthesized through multi-step organic reactions, and its sulfate form indicates the presence of a sulfate group, which can affect solubility and stability. As a pharmaceutical candidate, it may exhibit properties such as anti-cancer or anti-inflammatory effects, although specific biological activities would require empirical investigation. Its complex structure suggests potential for diverse interactions in biological systems, making it a subject of interest in medicinal chemistry and drug development.

Formula: C₃₁H₄₄N₆O₈S

Synonyms:

• 1-Piperazinecarboxamide, 4-[6-methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinyl]-N-[4-(1-methylethoxy)phenyl]-, sulfate (1:1)

Tandutinib sulfate

CAS: 387867-14-3

Tandutinib (MLN518) sulfate is an effective and selective inhibitor of FLT3, with an IC50 value of 0.22 μM. It also inhibits c-Kit and PDGFR, displaying IC50 values of 0.17 μM and 0.20 μM respectively. This compound can be utilized in the treatment of acute myeloid leukemia and has the capability to cross the blood-brain barrier.

Formula: C₃₁H₄₄N₆O₈S

Color and Shape: Solid

Molecular weight: 660.78

Ref: TM-T201851