CAS 388-51-2

metofenazate

Description:

Metofenazate, with the CAS number 388-51-2, is a chemical compound primarily used as an insecticide in agricultural applications. It belongs to the class of chemicals known as phenylureas and is characterized by its ability to disrupt the nervous system of target pests, making it effective against a variety of insects. Metofenazate is typically formulated as a soluble concentrate or emulsifiable concentrate, allowing for easy application in the field. The compound is known for its relatively low toxicity to non-target organisms, including mammals and beneficial insects, which makes it a preferred choice in integrated pest management strategies. Its mode of action involves interference with the insect's nervous system, leading to paralysis and eventual death. Additionally, metofenazate is stable under a range of environmental conditions, contributing to its effectiveness in pest control. However, like all pesticides, it should be used according to safety guidelines to minimize environmental impact and ensure human safety.

Formula: C₃₁H₃₆ClN₃O₅S

InChI: InChI=1/C31H36ClN3O5S/c1-37-26-19-22(20-27(38-2)30(26)39-3)31(36)40-18-17-34-15-13-33(14-16-34)11-6-12-35-24-7-4-5-8-28(24)41-29-10-9-23(32)21-25(29)35/h4-5,7-10,19-21H,6,11-18H2,1-3H3

InChI key: InChIKey=BAQLUVXNKOTTHU-UHFFFAOYSA-N

SMILES: C(CCN1CCN(CCOC(=O)C2=CC(OC)=C(OC)C(OC)=C2)CC1)N3C=4C(SC=5C3=CC=CC5)=CC=C(Cl)C4

Synonyms:

• 1-Piperazineethanol, 4-(3-(2-chlorophenothiazin-10-yl)propyl)-, 3,4,5-trimethoxybenzoate
• 2-(4-(3-(2-Chlorophenothiazin-10-yl)propyl)-1-piperazinyl)ethyl 3,4,5-trimethoxybenzoate
• 2-[4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl]ethyl 3,4,5-trimethoxybenzoate
• 2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethyl 3,4,5-trimethoxybenzoate
• Benzoic acid, 3,4,5-trimethoxy-, 2-(4-(3-(2-chlorophenothiazin-10-yl)propyl)-1-piperazinyl)ethyl ester
• Benzoic acid, 3,4,5-trimethoxy-, 2-[4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl]ethyl ester
• Brn 0773134
• Methophenazine
• Metofenazate [INN]
• Metofenazato
• Metofenazato [INN-Spanish]
• Metofenazatum
• Metofenazatum [INN-Latin]
• T 5
• Unii-27J5Ow8Ogt
• Metofenazate
• Metofenazate (base and/or unspecified salts)
• 3,4,5-Trimethoxybenzoic acid 2-[4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl]ethyl ester
• 522-23-6 (Difumarate)
• 3,4,5-Trimethoxybenzoic acid 2-[4-[3-(2-chloro-10H-phenothiazine-10-yl)propyl]piperazino]ethyl ester

Aurora B inhibitor 1

CAS: 388-51-2

Aurora B inhibitor 1

Purity: ≥98%

Molecular weight: 529.97g/mol

Ref: 54-BUP20417

Metofenazate-d9

Controlled Product

CAS: 388-51-2

Applications Metofenazate-d9, is the labeled analogue of Metofenazate (M225805), a novel phenothiazine antipsychotic agent. It has also been shown to have MDR1 inhibitory activity, which may serve as a basis of the development of an effective MDR1 inhibitor drug.
References Konya, A., et al.: Biochem. Biophys. Res. Commun., 346, 45 (2006);

Formula: C₃₁D₉H₂₇ClN₃O₅S

Color and Shape: Neat

Molecular weight: 607.208

Ref: TR-M225807

Metofenazate

Controlled Product

CAS: 388-51-2

Metofenazate is a synthetic drug that belongs to the class of pharmacological agents and has been used in the treatment of cancer. It is an aerosolized form of the drug, which is administered through inhalation. Metofenazate has been shown to have anticancer activity by inhibiting the growth of lung cancer cells. This drug also inhibits cyclic nucleotide phosphodiesterase, an enzyme that degrades cAMP, thereby blocking the production of prostaglandins and leukotrienes. The anti-inflammatory properties may be due to its ability to inhibit glucocorticoid receptors and reduce inflammation. Metofenazate can cause an occlusion in the myocardial infarct, causing a decrease in blood flow to this area.

Formula: C₃₁H₃₆ClN₃O₅S

Purity: Min. 95%

Molecular weight: 598.2 g/mol

Ref: 3D-AAA38851

Metofenazate

CAS: 388-51-2

Metofenazate is an selective inhibitor of calmodulin .

Formula: C₃₁H₃₆ClN₃O₅S

Purity: 98%

Color and Shape: Solid

Molecular weight: 598.15

Ref: TM-T12021