CAS 38821-53-3: Cephradine

Description: Cephradine is a semi-synthetic cephalosporin antibiotic, classified under the broader category of beta-lactam antibiotics. It is primarily used to treat various bacterial infections, particularly those caused by susceptible strains of gram-positive and some gram-negative bacteria. Cephradine exhibits a broad spectrum of antibacterial activity and is effective against respiratory tract infections, skin infections, and urinary tract infections. The compound is characterized by its stability against certain beta-lactamases, which enhances its efficacy against resistant bacterial strains. Cephradine is typically administered orally and is well-absorbed in the gastrointestinal tract. Its pharmacokinetics include a relatively short half-life, necessitating multiple doses throughout the day for optimal therapeutic effect. Common side effects may include gastrointestinal disturbances, allergic reactions, and, in rare cases, hematological abnormalities. As with other antibiotics, it is crucial to use cephradine judiciously to minimize the risk of developing antibiotic resistance.

Formula: C₁₆H₁₉N₃O₄S

InChI: InChI=1S/C16H19N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-3,6,10-11,15H,4-5,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1

InChI key: InChIKey=RDLPVSKMFDYCOR-UEKVPHQBSA-N

SMILES: O=C(O)C1=C(C)CSC2N1C(=O)C2NC(=O)C(N)C3=CCC=CC3

Synonyms:

• (6R,7R)-7-[[(2R)-2-Amino-2-(1,4-cyclohexadien-1-yl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7R)-7-{[(2R)-2-amino-2-(cyclohexa-1,4-dien-1-yl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R-(6Alpha,7))-((Amino-1,4-Cyclohexadien-1-Ylacetyl)Amino)-3-Methyl-8-Oxo-5-Thia-1-Azabicyclo(4.2.0)Oct-2-Ene-2-Carboxylic Acid
• (7R)-7-{[(2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[(amino-1,4-cyclohexadien-1-ylacetyl)amino]-3-methyl-8-oxo-, [6R-[6α,7β(R*)]]-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-2-amino-2-(1,4-cyclohexadien-1-yl)acetyl]amino]-3-methyl-8-oxo-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-amino-1,4-cyclohexadien-1-ylacetyl]amino]-3-methyl-8-oxo-, (6R,7R)-
• 7-[<span class="text-smallcaps">D</span>-α-Amino-(1,4-cyclohexadienyl)acetamide]-3-desacetoxycephalosphoranic acid
• 7-[D-α-Amino-(1,4-cyclohexadienyl)acetamide]-3-desacetoxycephalosphoranic acid
• Anspor
• Cefradex
• Cefradin
• Cefradina
• Cefrag
• Cefro
• Celex
• Cephradin
• Cephradine
• Cephradine Compacted
• Cephradine Micronised Powder
• Cesporan
• Desacetoxycephalosporanic Acid, 7-[D-2-Amino-2-(1,4-Cyclohexadienyl)Acetamido-
• Dimacef
• Easkacef
• Ecosporina
• Eskacef
• Lenzacef
• Lisacef
• Megacef
• Samedrin
• Sefril
• Sq 11436
• Velocef
• Velosef
• [6R-[6α,7β(R*)]]-7-Amino-1,4-cyclohexadien-1-ylacetyl)amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Cephradine Monohydrate

CAS: 38821-53-375975-70-1

• Formula: C₁₆H₁₉N₃O₄S·H₂O
• Purity: >96.0%(T)(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 367.43

Cefradine CRS

CAS: 38821-53-3

• Formula: C₁₆H₁₉N₃O₄S
• Color and Shape: White. Yellow. Powder.
• Molecular weight: 349.4048

Cefradine

CAS: 38821-53-3

• Formula: C₁₆H₁₉N₃O₄S
• Purity: 91.4%
• Color and Shape: Off White Crystalline Powder
• Molecular weight: 349.10963

Cefradine for peak identification CRS

CAS: 38821-53-3

• Formula: C₁₆H₁₉N₃O₄S
• Molecular weight: 349.4048

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2R)-amino-1,4-cyclohexadien-1-ylacetyl]amino]-3-methyl-8-oxo-,(6R,7R)-

CAS: 38821-53-3

• Formula: C₁₆H₁₉N₃O₄S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 349.4048

Cephradine

CAS: 38821-53-3

Cephradine (Anspor) is a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity.

• Formula: C₁₆H₁₉N₃O₄S
• Purity: 99.63%
• Color and Shape: White Crystalline Powder; Polymorphic Solid
• Molecular weight: 349.4

Cefradine-d5

CAS: 38821-53-3

• Formula: C₁₆H₁₄D₅N₃O₄S
• Color and Shape: White To Off-White Solid
• Molecular weight: 354.44

Cephradine

CAS: 38821-53-3

• Formula: C₁₆H₁₉N₃O₄S·H₂O
• Purity: ≥ 95.0% (anhydrous basis)
• Color and Shape: White or off-white powder
• Molecular weight: 349.40 (anhydrous)

Cefradine

CAS: 38821-53-3

• Formula: C₁₆H₁₉N₃O₄S
• Color and Shape: White To Off-White Solid
• Molecular weight: 349.41

Cefradine

CAS: 38821-53-3

• Formula: C₁₆H₁₉N₃O₄S
• Color and Shape: Neat
• Molecular weight: 349.40

Cefradine

CAS: 38821-53-3

• Formula: C₁₆H₁₉N₃O₄S
• Color and Shape: Neat
• Molecular weight: 349.40

Cephradine hydrate

CAS: 38821-53-3

• Formula: C₁₆H₁₇N₃O₄S·H₂O
• Color and Shape: Solid
• Molecular weight: 365.40g/mol

Cephradine

CAS: 38821-53-3

Applications Cephradine is a first generation cephalosporin antibiotic. Cephradine has broad spectrum of bactericidal activity …

• Formula: C₁₆H₁₉N₃O₄S
• Color and Shape: Neat
• Molecular weight: 349.40

Cephradine

CAS: 38821-53-3

Please enquire for more information about Cephradine including the price, delivery time and more detailed …

• Formula: C₁₆H₁₉N₃O₄S
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 349.41 g/mol

sodium (R)-2-((R)-((R)-2-amino-2-(cyclohexa-1,4-dien-1-yl)acetamido)(carboxylato)methyl)-5-methyl-3,6-dihydro-2H-1,3-thiazine-4-carboxylate

CAS: 38821-53-3

Applications Cephradine Acid is an impurity of Cephradine(C261800). Cephradine is a first generation cephalosporin antibiotic. …

• Formula: C₁₆H₁₉N₃Na₂O₅S
• Color and Shape: Neat
• Molecular weight: 411.384

Cephradine-d5

CAS: 38821-53-3

Applications Labelled Cephradine is a first generation cephalosporin antibiotic. Cephradine has broad spectrum of bactericidal …

• Formula: C₁₆H₁₄D₅N₃O₄S
• Color and Shape: Neat
• Molecular weight: 354.44