CAS 38821-53-3

Cephradine

Description:

Cephradine is a semi-synthetic cephalosporin antibiotic, classified under the broader category of beta-lactam antibiotics. It is primarily used to treat various bacterial infections, particularly those caused by susceptible strains of gram-positive and some gram-negative bacteria. Cephradine exhibits a broad spectrum of antibacterial activity and is effective against respiratory tract infections, skin infections, and urinary tract infections. The compound is characterized by its stability against certain beta-lactamases, which enhances its efficacy against resistant bacterial strains. Cephradine is typically administered orally and is well-absorbed in the gastrointestinal tract. Its pharmacokinetics include a relatively short half-life, necessitating multiple doses throughout the day for optimal therapeutic effect. Common side effects may include gastrointestinal disturbances, allergic reactions, and, in rare cases, hematological abnormalities. As with other antibiotics, it is crucial to use cephradine judiciously to minimize the risk of developing antibiotic resistance.

Formula: C₁₆H₂₁N₃O₅S

InChI: InChI=1/C16H19N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-3,6,10-11,15H,4-5,7,17H2,1H3,(H,18,20)(H,22,23)/t10?,11?,15-/m1/s1

InChI key: InChIKey=RDLPVSKMFDYCOR-UEKVPHQBSA-N

SMILES: O=C1N2[C@@]([C@@H]1NC([C@H](N)C=3CC=CCC3)=O)(SCC(C)=C2C(O)=O)[H]

Synonyms:

• (6R,7R)-7-[[(2R)-2-Amino-2-(1,4-cyclohexadien-1-yl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7R)-7-{[(2R)-2-amino-2-(cyclohexa-1,4-dien-1-yl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R-(6Alpha,7))-((Amino-1,4-Cyclohexadien-1-Ylacetyl)Amino)-3-Methyl-8-Oxo-5-Thia-1-Azabicyclo(4.2.0)Oct-2-Ene-2-Carboxylic Acid
• (7R)-7-{[(2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[(amino-1,4-cyclohexadien-1-ylacetyl)amino]-3-methyl-8-oxo-, [6R-[6α,7β(R*)]]-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-2-amino-2-(1,4-cyclohexadien-1-yl)acetyl]amino]-3-methyl-8-oxo-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-amino-1,4-cyclohexadien-1-ylacetyl]amino]-3-methyl-8-oxo-, (6R,7R)-
• 7-[<span class="text-smallcaps">D</span>-α-Amino-(1,4-cyclohexadienyl)acetamide]-3-desacetoxycephalosphoranic acid
• 7-[D-α-Amino-(1,4-cyclohexadienyl)acetamide]-3-desacetoxycephalosphoranic acid
• Anspor
• Cefradex
• Cefradin
• Cefradina
• Cefrag
• Cefro
• Celex
• Cephradin
• Cephradine
• Cephradine Compacted
• Cephradine Micronised Powder
• Cesporan
• Desacetoxycephalosporanic Acid, 7-[D-2-Amino-2-(1,4-Cyclohexadienyl)Acetamido-
• Dimacef
• Easkacef
• Ecosporina
• Eskacef
• Lenzacef
• Lisacef
• Megacef
• Samedrin
• Sefril
• Sq 11436
• Velocef
• Velosef
• [6R-[6α,7β(R*)]]-7-Amino-1,4-cyclohexadien-1-ylacetyl)amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• CEPHRADINE HYDRATE
• 7-[d-2-amino-2-(1,4-cyclohexadien-1-yl)acetamido]-3-methyl-8-oxo-5-thia-1-azab
• 7-[d-2-amino-2-(1,4-cyclohexadienyl)acetamide]desacetoxycephalosporanicacid
• CEFRADINE
• sq11436
• CEPHRADINE APPROX. 90% (HPLC)
• (6r-6alpha,7beta(r*)))-ien-1-ylacetyl)amino)-3-methyl-8-ox
• (6r-(6-alpha,7-beta(r*)))-ien-1-ylacetyl)amino)-3-methyl-8-oxo
• 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylicacid,7-((amino-1,4-cyclohexad

CEFRADINE CRS

CAS: 38821-53-3

CEFRADINE CRS

Formula: C₁₆H₁₉N₃O₄S

Color and Shape: White. Yellow. Powder.

Molecular weight: 349.4048

Ref: 41-C0690000

Cefradine

CAS: 38821-53-3

Cefradine

Formula: C₁₆H₁₉N₃O₄S

Purity: 91.4%

Color and Shape: Off-White

Molecular weight: 349.10963

Ref: 47-63

CEFRADINE FOR PEAK IDENTIFICATION CRS

CAS: 38821-53-3

CEFRADINE FOR PEAK IDENTIFICATION CRS

Formula: C₁₆H₁₉N₃O₄S

Molecular weight: 349.4048

Ref: 41-Y0000568

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2R)-amino-1,4-cyclohexadien-1-ylacetyl]amino]-3-methyl-8-oxo-,(6R,7R)-

CAS: 38821-53-3

Formula: C₁₆H₁₉N₃O₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 349.4048

Ref: IN-DA00ILHT

Cephradine

CAS: 38821-53-3

Cephradine (Anspor) is a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity.

Formula: C₁₆H₁₉N₃O₄S

Purity: 99.63%

Color and Shape: White Crystalline Powder; Polymorphic Solid

Molecular weight: 349.40

Ref: TM-T0199

Cephradine

CAS: 38821-53-3

Cephradine

Purity: ≥98%

Molecular weight: 349.4g/mol

Ref: 54-BUP17401

Cefradine

CAS: 38821-53-3

Formula: C₁₆H₁₉N₃O₄S

Color and Shape: White To Off-White Solid

Molecular weight: 349.41

Ref: 4Z-C-120001

Cephradine

CAS: 38821-53-3

Formula: C₁₆H₁₉N₃O₄S·H₂O

Purity: ≥ 95.0% (anhydrous basis)

Color and Shape: White or off-white powder

Molecular weight: 349.40 (anhydrous)

Ref: 7W-GA8023

Cefradine-d5

CAS: 38821-53-3

Formula: C₁₆H₁₄D₅N₃O₄S

Color and Shape: White To Off-White Solid

Molecular weight: 354.44

Ref: 4Z-C-120007

Cefradine

Controlled Product

CAS: 38821-53-3

Formula: C₁₆H₁₉N₃O₄S

Color and Shape: Neat

Molecular weight: 349.40

Ref: 86-MM0833.00

Cephradine (Standard)

CAS: 38821-53-3

Cephradine (Standard) is the standard substance of Cephradine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Cephradine (Anspor) is a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity.

Formula: C₁₆H₁₉N₃O₄S

Molecular weight: 349.40

Ref: TM-TMSM-0677

Cefradine

Controlled Product

CAS: 38821-53-3

Formula: C₁₆H₁₉N₃O₄S

Color and Shape: Neat

Molecular weight: 349.40

Ref: 04-CA11064800

Cephradine hydrate

CAS: 38821-53-3

Cephradine hydrate

Formula: C₁₆H₁₇N₃O₄S·H₂O

Color and Shape: Solid

Molecular weight: 365.40g/mol

Ref: 54-BIC0102

Cephradine

Controlled Product

CAS: 38821-53-3

Applications Cephradine is a first generation cephalosporin antibiotic. Cephradine has broad spectrum of bactericidal activity against infections caused by Streptococcus, Staphylococcus, Diplococcus pneumoniae, Escherichia, Klebsiella, Salmonella, and indole-negative Proteus.
References Poutsiaka, J.W. et al.: Prog. Chemother. (Antibacterial, Antiviral, Antineoplast.), Proc. Int. Congr. Chemother., 2, 142 (1974); Florey, K. et al.: Anal. Prof. Drug Subs., 5, 21 (1976);

Formula: C₁₆H₁₉N₃O₄S

Color and Shape: Off-White

Molecular weight: 349.40

Ref: TR-C261800

Cephradine

CAS: 38821-53-3

Cephradine is a first-generation cephalosporin antibiotic with action on bacterial cell wall synthesis and is used for treating bacterial infections like urinary tract infections, respiratory infections, and skin infections.

Formula: C₁₆H₁₉N₃O₄S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 349.41 g/mol

Ref: 3D-AA44691

Cephradine-d5

Controlled Product

CAS: 38821-53-3

Applications Labelled Cephradine is a first generation cephalosporin antibiotic. Cephradine has broad spectrum of bactericidal activity against infections caused by Streptococcus, Staphylococcus, Diplococcus pneumoniae, Escherichia, Klebsiella, Salmonella, and indole-negative Proteus.
References Poutsiaka, J.W. et al.: Prog. Chemother. (Antibacterial, Antiviral, Antineoplast.), Proc. Int. Congr. Chemother., 2, 142 (1974); Florey, K. et al.: Anal. Prof. Drug Subs., 5, 21 (1976);

Formula: C₁₆H₁₄D₅N₃O₄S

Color and Shape: Neat

Molecular weight: 354.44

Ref: TR-C261802

sodium (R)-2-((R)-((R)-2-amino-2-(cyclohexa-1,4-dien-1-yl)acetamido)(carboxylato)methyl)-5-methyl-3,6-dihydro-2H-1,3-thiazine-4-carboxylate

Controlled Product

CAS: 38821-53-3

Applications Cephradine Acid is an impurity of Cephradine(C261800). Cephradine is a first generation cephalosporin antibiotic. Cephradine has broad spectrum of bactericidal activity against infections caused by Streptococcus, Staphylococcus, Diplococcus pneumoniae, Escherichia, Klebsiella, Salmonella, and indole-negative Proteus
References Poutsiaka, J.W. et al.: Prog. Chemother. (Antibacterial, Antiviral, Antineoplast.), Proc. Int. Congr. Chemother., 2, 142 (1974); Florey, K. et al.: Anal. Prof. Drug Subs., 5, 21 (1976);

Formula: C₁₆H₁₉N₃Na₂O₅S

Color and Shape: Neat

Molecular weight: 411.384

Ref: TR-C261835

Cephradine

CAS: 38821-53-3

Formula: C₁₆H₁₉N₃O₄S

Molecular weight: 349.41

Ref: ST-EA-CP-A59021

Cefradine

CAS: 38821-53-3

Color and Shape: Neat

Ref: 61-FOR0833.00

Cephradine Monohydrate

CAS: 38821-53-3, 75975-70-1

Formula: C₁₆H₁₉N₃O₄S·H₂O

Purity: >96.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 367.43

Ref: 3B-C2988