CAS 3883-95-2

3-Bromosalicylic acid

Description:

3-Bromosalicylic acid is an organic compound characterized by the presence of both a bromine atom and a carboxylic acid functional group attached to a salicylic acid structure. Its molecular formula is C7H6BrO3, indicating it contains seven carbon atoms, six hydrogen atoms, one bromine atom, and three oxygen atoms. This compound typically appears as a white to off-white crystalline solid. It is known for its role in various chemical reactions, particularly in the synthesis of pharmaceuticals and agrochemicals. The bromine substituent at the meta position relative to the hydroxyl group influences its reactivity and solubility properties. 3-Bromosalicylic acid exhibits moderate solubility in polar solvents like water and ethanol, while being less soluble in non-polar solvents. Additionally, it may display biological activity, making it of interest in medicinal chemistry. As with many organic compounds, proper handling and safety precautions are essential due to potential toxicity and environmental impact.

Formula: C₇H₅BrO₃

InChI: InChI=1S/C7H5BrO3/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3,9H,(H,10,11)

InChI key: InChIKey=BHPSQWRVKOPSOQ-UHFFFAOYSA-N

SMILES: C(O)(=O)C1=C(O)C(Br)=CC=C1

Synonyms:

• 3-Bromosalicylic acid
• Benzoic Acid, 3-Bromo-2-Hydroxy-
• Salicylic acid, 3-bromo-
• 3-Bromo-2-hydroxybenzoic acid

3-Bromo-2-hydroxybenzoic acid

CAS: 3883-95-2

Formula: C₇H₅BrO₃

Purity: 96%

Color and Shape: Solid

Molecular weight: 217.0168

Ref: IN-DA00BYKN

3-Bromo-2-hydroxybenzoic acid

CAS: 3883-95-2

3-Bromo-2-hydroxybenzoic acid

Formula: C₇H₅BrO₃

Purity: ≥95%

Color and Shape: grey-yellow solid

Molecular weight: 217.02g/mol

Ref: 54-OR30793

3-Bromo-2-hydroxybenzoic acid

CAS: 3883-95-2

Formula: C₇H₅BrO₃

Purity: 96%

Color and Shape: Solid

Molecular weight: 217.018

Ref: 10-F076295

3-Bromo-2-hydroxybenzoic Acid

Controlled Product

CAS: 3883-95-2

Applications 3-Bromo-2-hydroxybenzoic Acid is a potential an intermediate formed in the synthesis of 3-[4-(2-Pyridylsulfamoyl)phenyl] Sulfasalazine (P995810), an impurity of Sulfasalazine (S699084), an anti-inflammatory (gastrointestinal). Sulfasalazine has been used in granulomatous colitis.
References Schroder, H., et al.: Clin. Pharmacol. Ther.,13, 539 (1972); McDonnell, J.P., et al.: Anal. Profiles Drug Subs., 5, 515 (1976); Klotz, U., et al.: Clin. Pharmacokinet.,10, 285 (1985)

Formula: C₃₁H₆₂O₃Si

Color and Shape: Neat

Molecular weight: 510.908

Ref: TR-B687620

3-Bromosalicylic acid

CAS: 3883-95-2

3-Bromosalicylic acid is a metabolite of salicylic acid and has shown clinical use in the treatment of cancer. 3-Bromosalicylic acid is synthesized from cyclohexanol and chlorine. It is a toxic compound that has been shown to inhibit protein synthesis in bacteria, including soil bacteria, but not in mammalian cells. This is due to its interaction with organic ligands that are present in the bacterial cell wall and not in mammalian cells. 3-Bromosalicylic acid also has been found to be a ligand for the receptor, PI3Kδ inhibitor, which inhibits tumor growth and metastasis by inhibiting phosphatidylinositol 3-kinase (PI3K) delta activity.

Formula: C₇H₅BrO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 217.02 g/mol

Ref: 3D-FB66982