CAS 38873-55-1

Furobufen

Description:

Furobufen is a non-steroidal anti-inflammatory drug (NSAID) that belongs to the class of compounds known as arylpropionic acids. It is primarily used for its analgesic and anti-inflammatory properties, making it effective in treating conditions such as pain and inflammation. The chemical structure of furobufen includes a furan ring, which contributes to its pharmacological activity. It is typically administered orally and is known to inhibit the cyclooxygenase (COX) enzymes, thereby reducing the synthesis of prostaglandins that mediate pain and inflammation. Furobufen exhibits moderate to high bioavailability and is metabolized in the liver, with its metabolites being excreted primarily through the urine. As with other NSAIDs, potential side effects may include gastrointestinal discomfort, cardiovascular risks, and renal impairment, particularly with long-term use. Due to its specific chemical properties and mechanism of action, furobufen is utilized in various therapeutic contexts, although it may not be as widely recognized as other NSAIDs.

Formula: C₁₆H₁₂O₄

InChI: InChI=1S/C16H12O4/c17-13(6-8-16(18)19)10-5-7-15-12(9-10)11-3-1-2-4-14(11)20-15/h1-5,7,9H,6,8H2,(H,18,19)

InChI key: InChIKey=LQVMQEYROPXMQH-UHFFFAOYSA-N

SMILES: C(CCC(O)=O)(=O)C=1C=C2C=3C(OC2=CC1)=CC=CC3

Synonyms:

• 2-Dibenzofuranbutanoic acid, gamma-oxo-
• 2-Dibenzofuranbutanoic acid, γ-oxo-
• 4-(Dibenzo[B,D]Furan-2-Yl)-4-Oxobutanoic Acid
• Ay 21367
• Brn 0250326
• Furobufen [USAN:INN]
• Furobufene
• Furobufene [French]
• Furobufene [INN-French]
• Furobufeno
• Furobufeno [INN-Spanish]
• Furobufeno [Spanish]
• Furobufenum
• Furobufenum [INN-Latin]
• Nsc 89140
• Unii-Hw206V7Tua
• gamma-Oxo-2-dibenzofuranbutyric acid
• γ-Oxo-2-dibenzofuranbutanoic acid
• γ-Oxo-2-dibenzofuranbutyric acid

Furobufen

CAS: 38873-55-1

Furobufen

Purity: ≥98%

Molecular weight: 268.26g/mol

Ref: 54-BUP08670

Furobufen

CAS: 38873-55-1

Furobufen is a compound with anti-inflammatory and analgesic activity and can be used in the study of arthritis.

Formula: C₁₆H₁₂O₄

Purity: 99.71%

Color and Shape: Solid

Molecular weight: 268.26

Ref: TM-T15360

Furobufen

CAS: 38873-55-1

Furobufen is a potent inhibitor of the enzyme c-Jun N-terminal kinase. It blocks the activity of this enzyme, which is involved in the regulation of cell proliferation, differentiation and apoptosis. Furobufen is therefore used as a research tool to study the role of c-Jun N-terminal kinase in these processes. Furobufen also binds to and inhibits protein interactions such as receptor and ligand interactions, and ion channel activity. Furobufen has been shown to act as an antagonist of potassium channels, which are important for regulating membrane potentials and cellular excitability.

Formula: C₁₆H₁₂O₄

Purity: Min. 95%

Molecular weight: 268.26 g/mol

Ref: 3D-NBA87355