CAS 38873-82-4

Prosta-5,13-dien-1-oicacid, 11,15-dihydroxy-9-oxo-, (5Z,11a,13E,15R)- (9CI)

Description:

Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-9-oxo-, (5Z,11a,13E,15R)-, commonly referred to by its CAS number 38873-82-4, is a synthetic compound that belongs to the class of prostaglandins, which are lipid compounds derived from fatty acids. This substance exhibits a complex structure characterized by multiple functional groups, including hydroxyl (-OH) groups and a ketone (C=O) group, contributing to its biological activity. Prostaglandins are known for their role in various physiological processes, including inflammation, blood flow regulation, and the modulation of immune responses. The specific stereochemistry indicated by the (5Z,11a,13E,15R) notation suggests a particular three-dimensional arrangement of atoms, which is crucial for its interaction with biological receptors. As a chemical entity, it may be utilized in research settings to study its effects on biological systems or to develop therapeutic agents targeting prostaglandin pathways. Its stability, solubility, and reactivity would depend on the surrounding conditions and the presence of other chemical species.

Formula: C₂₀H₃₂O₅

Synonyms:

• (15R)-Prostaglandin E2
• 15-Epiprostaglandin E2
• 15b-PGE2
• 15-epi-Prostaglandin E2
• (15R)-PGE2
• Dinoprostone EP Impurity A
• 15(R)-PROSTAGLANDIN E2
• XEYBRNLFEZDVAW-GKEZHNTDSA-N
• (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E)-(3R)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid (15-epiPGE2
• 9-OXO-11ALPHA,15R-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID
• 15-EPI PGE2

Alprostadil (Prostaglandin E1) Impurity 7 ((15R)-PGE2)

CAS: 38873-82-4

Formula: C₂₀H₃₂O₅

Molecular weight: 352.471

Ref: 4Z-P-144037

15(R)​-​Prostaglandin E2

Controlled Product

CAS: 38873-82-4

Formula: C₂₀H₃₂O₅

Color and Shape: Neat

Molecular weight: 352.465

Ref: TR-P888910

Dinoprostone EP Impurity A

CAS: 38873-82-4

Formula: C₂₀H₃₂O₅

Molecular weight: 352.47

Ref: ST-EA-CP-D117001

15(R)-Prostaglandin E2

CAS: 38873-82-4

15(R)-Prostaglandin E2, the C-15 epimer of the more physiologically abundant 15(S)-PGE2 (sc-201225) isomer, is produced mainly from arachidonic acid (sc-200770) via the action of COX and PGES enzymes. Present in nearly all cell types, PGE2 interacts with four distinct receptors, EP1 to EP4, leading to a wide range of biological effects. However, 15(R)-Prostaglandin E2 exhibits significantly lower efficacy in most biological assays compared to its 15(S) counterpart. Notably, acid catalyzed epimerization can transform 15(R)-Prostaglandin E2 into the more active 15(S)-Prostaglandin E2 form.

Formula: C₂₀H₃₂O₅

Color and Shape: Solid

Molecular weight: 352.471

Ref: TM-T84587