CAS 3891-07-4

N-(2-Hydroxyethyl)phthalimide

Description:

N-(2-Hydroxyethyl)phthalimide, with the CAS number 3891-07-4, is an organic compound that belongs to the class of phthalimides. It features a phthalimide moiety substituted with a 2-hydroxyethyl group, which contributes to its solubility and reactivity. This compound is typically a white to off-white solid at room temperature and is soluble in polar solvents such as water and alcohols due to the presence of the hydroxyl group. N-(2-Hydroxyethyl)phthalimide is known for its applications in organic synthesis, particularly as a reagent in the preparation of various derivatives and as an intermediate in the production of pharmaceuticals and agrochemicals. It exhibits moderate stability under standard conditions but may undergo hydrolysis or other reactions in the presence of strong acids or bases. Additionally, it is important to handle this compound with care, as it may pose health risks if ingested or inhaled, necessitating appropriate safety measures during use.

Formula: C₁₀H₉NO₃

InChI: InChI=1S/C10H9NO3/c12-6-5-11-9(13)7-3-1-2-4-8(7)10(11)14/h1-4,12H,5-6H2

InChI key: InChIKey=MWFLUYFYHANMCM-UHFFFAOYSA-N

SMILES: O=C1C=2C(C(=O)N1CCO)=CC=CC2

Synonyms:

• 1H-Isoindole-1,3(2H)-dione, 2-(2-hydroxyethyl)-
• 2-(2-Hydroxyethyl)-1H-Isoindole-1,3(2H)-Dione
• 2-(2-Hydroxyethyl)-1H-Isoindole-3(2H)-Dione
• 2-(2-Hydroxyethyl)-2,3-dihydro-1H-isoindole-1,3-dione
• 2-(2-Hydroxyethyl)isoindole-1,3-dione
• 2-(2-Hydroxyethyl)isoindoline-1,3-dione
• 2-(N-Phthalimidyl)ethyl alcohol
• 2-Hydroxyethylphthalimide
• 2-Phthalimidoethanol
• Akos Bbs-00004429
• N-(Beta-Hydroxyethyl)Phthalimide
• N-Hydroxyethylphthalimide
• N-hydroethyl phthalimide
• NSC 2773
• NSC 50624
• Phthalimide, N-(2-hydroxyethyl)-
• Timtec-Bb Sbb003638

N-(2-Hydroxyethyl)phthalimide

CAS: 3891-07-4

Formula: C₁₀H₉NO₃

Purity: >98.0%(HPLC)(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 191.19

Ref: 3B-H0245

N-(2-Hydroxyethyl)phthalimide, 98+%

CAS: 3891-07-4

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₀H₉NO₃

Purity: 98+%

Color and Shape: White to cream, Crystals or powder or crystalline powder or lumps

Molecular weight: 191.19

Ref: 02-A14259

2-(2-Hydroxyethyl)isoindoline-1,3-dione

CAS: 3891-07-4

Formula: C₁₀H₉NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 191.1834

Ref: IN-DA001IF5

N-(2-Hydroxyethyl)phthalimide

CAS: 3891-07-4

N-(2-Hydroxyethyl)phthalimide

Formula: C₁₀H₉NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 191.18336

Ref: 54-OR923052

Amlodipine Impurity 6 (N-(2-Hydroxyethyl)phthalimide)

CAS: 3891-07-4

Formula: C₁₀H₉NO₃

Color and Shape: White To Off-White Solid

Molecular weight: 191.19

Ref: 4Z-A-0828

N-(2-Hydroxyethyl)phthalimide

Controlled Product

CAS: 3891-07-4

Impurity Amlodipine Impurity 6
Applications N-(2-Hydroxyethyl)phthalimide is used as a reagent to synthesize (-)-R-rolipram is a phosphodiesterase 4 inhibitor that is used to treat depression. N-(2-Hydroxyethyl)phthalimide is also used as a reagent to synthesize FR252921, a compound that acts as an immunosuppressant. Amlodipine Impurity 6
References Egawa, T., et al.: Japan. J. Pharm., 75, 275 (1997); Horiuchi, M., et al.: Nat. Prod. Res., 20, 161 (2006); Russell, F., et al.: Angew. Chem. Int. Edit., 46, 4527 (2007); Zeller, E., et al.: Pharma., 17, 188 (1984)

Formula: C₁₀H₉NO₃

Color and Shape: Neat

Molecular weight: 191.18

Ref: TR-H949490

2-(2-Hydroxyethyl)isoindoline-1,3-dione

CAS: 3891-07-4

Formula: C₁₀H₉NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 191.186

Ref: 10-F225536

N-(2-Hydroxyethyl)phthalimide

CAS: 3891-07-4

2-(2-Hydroxyethyl)isoindoline-1,3-dione

Formula: C₁₀H₉NO₃

Purity: 98%

Molecular weight: 191.18

Ref: IN-DG20595

Amlodipine Impurity 6

CAS: 3891-07-4

Formula: C₁₀H₉NO₃

Molecular weight: 191.19

Ref: ST-EA-CP-A5052