CAS 38964-33-9

N-Formylloline

Description:

N-Formylloline, with the CAS number 38964-33-9, is a chemical compound that belongs to the class of alkaloids, specifically derived from the loline family. It is characterized by its structural features, which include a pyrrolidine ring and a formyl group, contributing to its unique reactivity and properties. This compound is typically found in certain plant species and has garnered interest due to its potential biological activities, including antimicrobial and insecticidal properties. N-Formylloline is often studied for its role in plant defense mechanisms and its potential applications in agriculture and medicine. Its solubility and stability can vary depending on the solvent and environmental conditions, which is important for its practical applications. As with many alkaloids, it may exhibit a range of physiological effects, making it a subject of interest in pharmacological research. Overall, N-Formylloline represents a fascinating area of study within natural product chemistry and its implications in various fields.

Formula: C₉H₁₄N₂O₂

InChI: InChI=1S/C9H14N2O2/c1-10(5-12)8-7-4-11-3-2-6(13-7)9(8)11/h5-9H,2-4H2,1H3

InChI key: InChIKey=YHLKXYXFUCTURZ-UHFFFAOYSA-N

SMILES: N(C=O)(C)C1C2C3OC1CN2CC3

Synonyms:

• N-Formylloline
• N-[(2R,3R,3aS,4S,6aS)-Hexahydro-2,4-methano-4H-furo[3,2-b]pyrrol-3-yl]-N-methylformamide
• 2,4-Methano-4H-furo[3,2-b]pyrrole, formamide deriv.
• Formamide, N-(hexahydro-2,4-methano-4H-furo[3,2-b]pyrrol-3-yl)-N-methyl-, [2R-(2α,3α,3aβ,4α,6aβ)]-
• Formamide, N-[(2R,3R,3aS,4S,6aS)-hexahydro-2,4-methano-4H-furo[3,2-b]pyrrol-3-yl]-N-methyl-

N-Formylloline

CAS: 38964-33-9

Formula: C₉H₁₄N₂O₂

Molecular weight: 182.22

Ref: 4Z-L-155006

N-Formylloline-d3

CAS: 38964-33-9

Formula: C₉H₁₁D₃N₂O₂

Molecular weight: 185.24

Ref: 4Z-L-155007

N-Formylloline-d3

Controlled Product

CAS: 38964-33-9

Stability Hygroscopic
Applications N-Formylloline-d3 is the labelled analog of N-Formyllonline, a pyrrolizidine alkaloid found in significant concentrations in tall fescue plants. N-Formyllonline, like many pyrrolizidine alkaloids are naturally occuring insect-deterrant compounds for protective purposes. N-Formyllonline have also been found to bind and activate D2 dopamine receptor in cell culture.
References Patchett, B., et al.: New. Zealand. Agri. Rsch., 54, 303 (2011); Tofern, B., et al.: Phytochem., 51, 1177 (1999); Larson, B.T., et al.: J. Animal. Sci., 77, 942 (1999);

Formula: C₉H₁₁D₃N₂O₂

Color and Shape: Neat

Molecular weight: 185.24

Ref: TR-F700582

N-Formylloline

CAS: 38964-33-9

N-Formylloline is a kinase inhibitor analog that has been developed for medicinal use as an anti-tumor agent. It works by inhibiting protein kinases, which are enzymes involved in cell cycle regulation and cancer cell growth. N-Formylloline has shown promising results in inhibiting the proliferation of cancer cells and inducing apoptosis, making it a potential candidate for cancer treatment. This compound has been studied extensively in Chinese hamster ovary cells and human urine samples, where it demonstrated potent inhibition of kinase activity. N-Formylloline is a highly effective inhibitor that may have significant potential as an anticancer agent.

Formula: C₉H₁₄N₂O₂

Purity: Min. 95%

Molecular weight: 182.22 g/mol

Ref: 3D-NBA96433