CAS 390-28-3: Methoxamine

Description: Methoxamine, with the CAS number 390-28-3, is a chemical compound classified as a sympathomimetic agent. It is primarily known for its role as a vasopressor, which means it can constrict blood vessels and increase blood pressure. Methoxamine acts primarily on alpha-adrenergic receptors, leading to increased vascular resistance and reduced heart rate. This compound is typically used in clinical settings to manage hypotension, particularly during anesthesia. Methoxamine is a white to off-white crystalline powder that is soluble in water and exhibits a relatively stable profile under standard conditions. Its pharmacological effects are characterized by a rapid onset and a duration that can vary based on dosage and administration route. As with many sympathomimetics, caution is advised in patients with cardiovascular issues, as it can exacerbate conditions like hypertension or arrhythmias. Overall, Methoxamine is a valuable agent in emergency medicine and anesthesiology, but its use must be carefully monitored to avoid adverse effects.

Formula: C₁₁H₁₇NO₃

InChI: InChI=1S/C11H17NO3/c1-7(12)11(13)9-6-8(14-2)4-5-10(9)15-3/h4-7,11,13H,12H2,1-3H3

InChI key: InChIKey=WJAJPNHVVFWKKL-UHFFFAOYSA-N

SMILES: OC(C1=CC(OC)=CC=C1OC)C(N)C

Synonyms:

• 2-Amino-1-(2,5-dimethoxyphenyl)propan-1-ol
• Benzyl alcohol, α-(1-aminoethyl)-2,5-dimethoxy-
• Methoxamin
• Methoxamine
• Metoxamina
• α-(1-Aminoethyl)-2, 5-dimethoxybenzyl alcohol
• α-(1-Aminoethyl)-2,5-dimethoxybenzenemethanol
• α-(1-Aminoethyl)-2,5-dimethoxybenzyl alcohol
• Benzenemethanol, α-(1-aminoethyl)-2,5-dimethoxy-

Methoxamine HCl (Mixture of Diastereomers)

CAS: 390-28-361-16-5

• Formula: C₁₁H₁₇NO₃·HCl
• Molecular weight: 211.26 36.46

2-Amino-1-(2,5-dimethoxyphenyl)propan-1-ol

CAS: 390-28-3

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• Formula: C₁₁H₁₇NO₃
• Purity: Min. 95%
• Molecular weight: 211.26 g/mol