CAS 3902-71-4

Trimethylpsoralen

Description:

Trimethylpsoralen (TMP) is a chemical compound belonging to the class of psoralens, which are known for their ability to intercalate with DNA and form cross-links upon exposure to ultraviolet (UV) light. It is characterized by its molecular structure, which includes three methyl groups attached to the psoralen core, enhancing its solubility and reactivity. TMP is typically a colorless to pale yellow crystalline solid and is soluble in organic solvents such as ethanol and dimethyl sulfoxide (DMSO), but has limited solubility in water. This compound is primarily used in photochemotherapy, particularly for treating skin conditions like psoriasis and vitiligo, as it enhances the effects of UV light therapy. Additionally, TMP has applications in research, particularly in studies involving DNA interactions and photobiology. Due to its photosensitizing properties, caution is advised when handling TMP, as it can cause skin sensitization and other adverse effects upon UV exposure.

Formula: C₁₄H₁₂O₃

InChI: InChI=1S/C14H12O3/c1-7-4-12(15)17-14-9(3)13-10(6-11(7)14)5-8(2)16-13/h4-6H,1-3H3

InChI key: InChIKey=FMHHVULEAZTJMA-UHFFFAOYSA-N

SMILES: CC=1C2=C(C=C3C1OC(C)=C3)C(C)=CC(=O)O2

Synonyms:

• 5-Benzofuranacrylic acid, 6-hydroxy-β,2,7-trimethyl-, δ-lactone
• 4,5′,8-Trimethylpsoralen
• 2,5,9-Trimethyl-7H-furo[3,2-g][1]benzopyran-7-one
• Trioxsalen
• 7H-Furo[3,2-g][1]benzopyran-7-one, 2,5,9-trimethyl-

Trioxsalen

CAS: 3902-71-4

Formula: C₁₄H₁₂O₃

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 228.25

Ref: 3B-T2267

4,5',8-Trimethylpsoralen, 99%

CAS: 3902-71-4

4,5',8-Trimethylpsoralen is used for treatment of psoriasis, and as a photochemical crosslinker of DNA used as a probe for nucleic acid structure, used to crosslink DNA onto mica surfaces, mutagenesis of N2 worms. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar p

Formula: C₁₄H₁₂O₃

Purity: 99%

Molecular weight: 228.25

Ref: 02-J63226

TRIOXSALEN

CAS: 3902-71-4

Formula: C₁₄H₁₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 228.2433

Ref: IN-DA003V59

Trioxsalen

CAS: 3902-71-4

Trioxsalen

Purity: 98%

Molecular weight: 228.25g/mol

Ref: 54-OR1024247

Trioxsalen

CAS: 3902-71-4

Trioxsalen

Purity: ≥98%

Molecular weight: 228.24g/mol

Ref: 54-BUP13950

Trioxsalen

CAS: 3902-71-4

Formula: C₁₄H₁₂O₃

Molecular weight: 228.25

Ref: 7W-GL4271

Trioxysalen

CAS: 3902-71-4

Formula: C₁₄H₁₂O₃

Color and Shape: Neat

Molecular weight: 228.24

Ref: 04-C17892400

Trioxsalen

CAS: 3902-71-4

Formula: C₁₄H₁₂O₃

Molecular weight: 228.25

Ref: 4Z-T-434001

Trioxsalen

CAS: 3902-71-4

Trioxsalen (Trioxysalen) is a furanocoumarin and a psoralen derivative, in conjunction with UV-A for phototherapy treatment of vitiligo and hand eczema.

Formula: C₁₄H₁₂O₃

Purity: 98.96% - 99.41%

Color and Shape: Crystalline Powder

Molecular weight: 228.24

Ref: TM-T4558

Trioxsalen

CAS: 3902-71-4

Lactone

Formula: C₁₄H₁₂O₃

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 228.25

Ref: 5G-80322

2,5,9-trimethyl-7H-furo[3,2-g]chromen-7-one

CAS: 3902-71-4

Purity: 99.0%

Color and Shape: Solid

Molecular weight: 228.2469940185547

Ref: 10-F358125

Trioxysalen

Controlled Product

CAS: 3902-71-4

Applications Trioxysalen, is used for visualization of genomic interstrand cross-links localized by laser photoactivation. It has been also been used to crosslink DNA onto mica surfaces.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Thazhathveetill, et al.: Bioconjugare Chem., 18 (2), 431 (2007); Musdal, Y., et al.: Chem. Bio. Interac., 205, 53 (2013);

Formula: C₁₄H₁₂O₃

Color and Shape: Neat

Molecular weight: 228.24

Ref: TR-T806580

4,5',8-Trimethylpsoralen

CAS: 3902-71-4

4,5',8-Trimethylpsoralen is a fatty acid that can be synthesized from para-aminobenzoic acid. It has been shown to have carcinogenic potential in vitro and in vivo. 4,5',8-Trimethylpsoralen inhibits transcription by binding to DNA polymerase II and III. This inhibition prevents the production of RNA and protein synthesis, leading to cell death. 4,5',8-Trimethylpsoralen also inhibits DNA synthesis by binding to the enzyme DNA gyrase and topoisomerase IV. It is not active against some bacteria that are resistant to other drugs due to the presence of mutations in their genes encoding for the target enzymes. 4,5',8-Trimethylpsoralen has been shown to inhibit autoimmune diseases such as arthritis and lupus erythematosus.br>br>4,5',8-Trimethylpsoralen is most commonly used as

Formula: C₁₄H₁₂O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 228.24 g/mol

Ref: 3D-FT47227

Trioxsalen (DISCONTINUED)

CAS: 3902-71-4

Aromatic heterocyclic pesticides with oxygen hetero-atom(s) only, nesoi

Formula: C₁₄H₁₂O₃

Color and Shape: White Crystals

Molecular weight: 228.07864

Ref: 45-1693009