CAS 39025-23-5
:Z-Guggulsterone
Description:
Z-Guggulsterone, with the CAS number 39025-23-5, is a naturally occurring steroidal compound derived from the resin of the Commiphora mukul tree, commonly known as guggul. This compound is classified as a phytosterol and is known for its potential therapeutic properties, particularly in traditional medicine. Z-Guggulsterone exhibits a range of biological activities, including anti-inflammatory, antioxidant, and lipid-regulating effects, which have garnered interest in the fields of pharmacology and nutrition. It is often studied for its potential role in weight management and cholesterol regulation. The compound is characterized by its specific stereochemistry, which contributes to its biological activity. Z-Guggulsterone is typically found in the form of a solid or crystalline substance and is soluble in organic solvents but has limited solubility in water. Its safety and efficacy are subjects of ongoing research, and while it is available as a dietary supplement, users should consult healthcare professionals before use, especially in conjunction with other medications or health conditions.
Formula:C21H28O2
InChI:InChI=1S/C21H28O2/c1-4-16-19(23)12-18-15-6-5-13-11-14(22)7-9-20(13,2)17(15)8-10-21(16,18)3/h4,11,15,17-18H,5-10,12H2,1-3H3/b16-4+/t15-,17+,18+,20+,21-/m1/s1
InChI key:InChIKey=WDXRGPWQVHZTQJ-OSJVMJFVSA-N
SMILES:C[C@@]1\2[C@]([C@]3([C@@]([C@]4(C)C(CC3)=CC(=O)CC4)(CC1)[H])[H])(CC(=O)/C2=C\C)[H]
Synonyms:- (17Z)-Guggulsterone
- (17Z)-Pregna-4,17(20)-diene-3,16-dione
- (8xi,9xi,14xi,17E)-pregna-4,17-diene-3,16-dione
- 4,17(20)-cis-Pregnadiene-3,6-dione
- Z-Guggulsterone
- cis-Guggulsterone
- pregna-4,17-diene-3,16-dione, (8xi,9xi,14xi,17E)-
- Pregna-4,17(20)-diene-3,16-dione, (17Z)-
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Found 10 products.
(Z)-Guggulsterone
CAS:<p>(Z)-Guggulsterone triggers apoptosis in prostate cancer cells and blocks angiogenesis by inhibiting VEGF pathways.</p>Formula:C21H28O2Purity:98.93% - 99.72%Color and Shape:SolidMolecular weight:312.45Guggulsterone z
CAS:Alicyclic ketoneFormula:C21H28O2Purity:≥ 90.0 % (HPLC)Color and Shape:CrystalsMolecular weight:312.45(Z)-Guggulsterone
CAS:Controlled Product<p>Applications (Z)-Guggulsterone acts as an α-glucosidase inhibitor also known as a hypolipidemic agent.<br>References Yang, D. et al.: J. Lipid Res., 53, 529 (2012); El-Mekkawy, S. et al.: Nat. Prod. Res., 27, 146 (2013);<br></p>Formula:C21H28O2Color and Shape:NeatMolecular weight:312.45Z-Guggulsterone
CAS:Controlled Product<p>Guggulsterone is a natural product that has been shown to inhibit the activity of DNA polymerase and thus, prevent the synthesis of RNA. It also inhibits the binding of transcription factors, such as NF-κB, to DNA. Guggulsterone has been found to be effective in treating chronic liver diseases and other conditions associated with oxidative stress. It also has anti-inflammatory properties due to its ability to suppress pro-inflammatory cytokines such as IL-1β and IL-6, which are regulated by toll-like receptor signaling pathways. Guggulsterone also reduces cholesterol absorption through inhibition of the enzyme HMG-CoA reductase.</p>Formula:C21H28O2Purity:Min. 95%Molecular weight:312.45 g/molGuggulsterone Z
CAS:Cyclanic, cyclenic or cycloterpenic ketones without othFormula:C21H28O2Color and Shape:White Crystalline PowderMolecular weight:312.20893
