CAS 39025-24-6: (-)-(E)-Guggulsterone

Description: (-)-(E)-Guggulsterone, with the CAS number 39025-24-6, is a naturally occurring steroidal compound derived from the resin of the Commiphora mukul tree, commonly known as guggul. This compound is characterized by its dual isomeric forms, with the (-)-(E) configuration being biologically active. Guggulsterone is known for its potential therapeutic properties, particularly in traditional medicine, where it has been used for its anti-inflammatory and lipid-lowering effects. Chemically, it features a steroid backbone with specific functional groups that contribute to its biological activity. The compound has garnered interest in pharmacological research for its role in modulating cholesterol levels and its potential effects on metabolic disorders. Additionally, guggulsterone has been studied for its possible anticancer properties and its influence on thyroid function. Its solubility and stability can vary depending on the formulation, which is important for its application in dietary supplements and herbal remedies. Overall, (-)-(E)-Guggulsterone represents a significant compound in both traditional and modern medicinal contexts.

Formula: C₂₁H₂₈O₂

InChI: InChI=1S/C21H28O2/c1-4-16-19(23)12-18-15-6-5-13-11-14(22)7-9-20(13,2)17(15)8-10-21(16,18)3/h4,11,15,17-18H,5-10,12H2,1-3H3/b16-4-/t15-,17+,18+,20+,21-/m1/s1

InChI key: InChIKey=WDXRGPWQVHZTQJ-AUKWTSKRSA-N

SMILES: O=C1C=C2CCC3C4CC(=O)C(=CC)C4(C)CCC3C2(C)CC1

Synonyms:

• (-)-(E)-Guggulsterone
• (17E)-Pregna-4,17(20)-diene-3,16-dione
• (17E)-pregna-4,17-diene-3,16-dione
• 4,17(20)-(trans)-Pregnadiene-3,16-dione
• E-Guggulsteron
• Guggulsterone E
• trans-Guggulsterone
• Pregna-4,17(20)-diene-3,16-dione, (17E)-

Pregna-4,17(20)-diene-3,16-dione, (17E)-

CAS: 39025-24-6

• Formula: C₂₁H₂₈O₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 312.4458

(E)-Guggulsterone

CAS: 39025-24-6

• Formula: C₂₁H₂₈O₂
• Purity: ≥ 95.0%
• Color and Shape: White to off-white powder
• Molecular weight: 312.45

(E)-Guggulsterone

CAS: 39025-24-6

• Formula: C₂₁H₂₈O₂
• Purity: 95%~99%
• Molecular weight: 312.453

(E)-Guggulsterone

CAS: 39025-24-6

Bile acids aid fat digestion, originate from cholesterol, activate FXR, and can be toxic. Guggulsterone …

• Formula: C₂₁H₂₈O₂
• Color and Shape: Solid
• Molecular weight: 312.45

(E)-Guggulsterone

CAS: 39025-24-6

• Formula: C₂₁H₂₈O₂
• Molecular weight: 312.45

Guggulsterone e

CAS: 39025-24-6

Alicyclic ketone

• Formula: C₂₁H₂₈O₂
• Purity: ≥ 90.0 % (HPLC)
• Color and Shape: Crystals
• Molecular weight: 312.45

(E)-Guggulsterone

CAS: 39025-24-6

Applications (E)-Guggulsterone acts as an α-glucosidase inhibitor also known as a hypolipidemic agent. References Yang, …

• Formula: C₂₁H₂₈O₂
• Color and Shape: White To Off-White
• Molecular weight: 312.45

(E)-Guggulsterone

CAS: 39025-24-6

(E)-Guggulsterone is a phytosteroid, which is a bioactive compound derived from the resin of the …

• Formula: C₂₁H₂₈O₂
• Purity: Min. 98 Area-%
• Color and Shape: Powder
• Molecular weight: 312.45 g/mol