CAS 39070-14-9

1-Methyl-2-nitro-1H-imidazole-5-methanol

Description:

1-Methyl-2-nitro-1H-imidazole-5-methanol, with the CAS number 39070-14-9, is a chemical compound that features a nitro group and a hydroxymethyl group attached to an imidazole ring. This compound is characterized by its heterocyclic structure, which includes nitrogen atoms in the ring, contributing to its potential biological activity. The presence of the nitro group typically imparts unique reactivity and can influence the compound's solubility and stability. The hydroxymethyl group may enhance its polarity, affecting its interactions in various chemical environments. This compound is of interest in medicinal chemistry and may exhibit properties relevant to pharmacology, such as antimicrobial or antifungal activities. Its synthesis and characterization involve standard organic chemistry techniques, and it may be utilized in research settings to explore its potential applications in drug development or as a biochemical probe. Safety data should be consulted for handling and usage, as compounds with nitro groups can pose specific hazards.

Formula: C₅H₇N₃O₃

InChI: InChI=1S/C5H7N3O3/c1-7-4(3-9)2-6-5(7)8(10)11/h2,9H,3H2,1H3

InChI key: InChIKey=WXSSUDRHAJTESR-UHFFFAOYSA-N

SMILES: N(=O)(=O)C=1N(C)C(CO)=CN1

Synonyms:

• 1-Methyl-2-nitro-1H-imidazole-5-methanol
• 1-Methyl-2-nitroimidazole-5-methanol
• SR 2521
• L 8938
• 1H-Imidazole-5-methanol, 1-methyl-2-nitro-
• 106964
• (3-METHYL-2-NITRO-3H-IMIDAZOL-4-YL)-METHANOL hcl
• EOS-61725
• (3-METHYL-2-NITRO-3H-IMIDAZOL-4-YL)-METHANOL
• (3-Methyl-2-nitro-3H-imidazol-4-yl)methanol≥ 95% (NMR)
• (3-Methyl-2-nitro-3H-iMidazol-4-yl)
• 1H-Imidazole-5-methanol, 1-methyl-2-nitro- (9CI)
• 5-(Hydroxymethyl)-1-methyl-2-nitroimidazole
• (3-METHYL-2-NITRO-3H-IMIDAZOL-4-YL)-METHANOL-7
• 1-methyl-2-nitro-5-hydroxymethylimidazole
• (3-methyl-2-nitro-4-imidazolyl)methanol
• (1-Methyl-2-nitro-1H-iMidazol-5-yl)Methanol
• Nsc307224

(3-METHYL-2-NITRO-3H-IMIDAZOL-4-YL)-METHANOL

CAS: 39070-14-9

Formula: C₅H₇N₃O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 157.1274

Ref: IN-DA00BYVJ

(1-Methyl-2-nitro-1H-imidazol-5-yl)methanol

CAS: 39070-14-9

(1-Methyl-2-nitro-1H-imidazol-5-yl)methanol

Purity: 98%

Molecular weight: 157.13g/mol

Ref: 54-OR73777

(1-Methyl-2-nitro-1H-imidazol-5-yl)methanol

CAS: 39070-14-9

Formula: C₅H₇N₃O₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 157.129

Ref: 10-F240695

(3-Methyl-2-nitro-3H-imidazol-4-yl)methanol

Controlled Product

CAS: 39070-14-9

Applications (3-Methyl-2-nitro-3H-imidazol-4-yl)methanol is a chemical reagent used in the synthesis of prodrugs such as those targetting hypoxic tissues.
References Everett, S. et al.: Bioorg. Med. Chem. Lett., 9, 1267 (1999); Hay, M. et al.: Bioorg. Med. Chem., 13, 4043 (2005);

Formula: C₅H₇N₃O₃

Color and Shape: Light Yellow

Molecular weight: 157.13

Ref: TR-M323820

(3-Methyl-2-nitro-3H-imidazol-4-yl)methanol

CAS: 39070-14-9

3-Methyl-2-nitro-3H-imidazol-4-yl)methanol is a fluorescent probe that can be used to detect hypoxic tumor cells. It has been shown to selectively react with the methylethyl group in Trichomonas vaginalis. 3-Methyl-2-nitro-3H-imidazol-4-yl)methanol is bioreductive and can be activated by nitro groups in proteins, which are found in the active site of enzymes such as bacterial dna gyrase. This probe has been shown to bind to the sn38 position of bacterial DNA, but not mammalian DNA.

Formula: C₅H₇N₃O₃

Purity: Min. 95%

Molecular weight: 157.13 g/mol

Ref: 3D-FM51338