CAS: 391210-10-9 - N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide

Formula: C₁₆H₁₄F₃IN₂O₄

InChI: InChI=1S/C16H14F3IN2O4/c17-11-3-2-10(16(25)22-26-7-9(24)6-23)15(14(11)19)21-13-4-1-8(20)5-12(13)18/h1-5,9,21,23-24H,6-7H2,(H,22,25)/t9-/m1/s1

InChI key: InChIKey=SUDAHWBOROXANE-SECBINFHSA-N

SMILES: O=C(NOCC(O)CO)C1=CC=C(F)C(F)=C1NC2=CC=C(I)C=C2F

Synonyms:

• Benzamide, N-[(2R)-2,3-dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-
• Mirdametinib
• N-(2,3-dihydroxypropoxy)-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide
• N-[((R)-2,3-Dihydroxypropyl)oxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide
• N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-(2-fluoro-4-iodoanilino)benzamide
• N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide
• Pd 0325901
• Pd 03525901
• Pd 325901
• Pd 901
• Pd325901

N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide

CAS: 391210-10-9

• Formula: C₁₆H₁₄F₃IN₂O₄
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 482.1930

PD 0325901

CAS: 391210-10-9

• Formula: C₁₆H₁₄F₃IN₂O₄
• Purity: >97.0%(T)(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 482.20

Mirdametinib

CAS: 391210-10-9

Mirdametinib (PD325901) is an MEK inhibitor (IC50=0.33 nM) with selective, non-ATP-competitive, and oral activity.

• Formula: C₁₆H₁₄F₃IN₂O₄
• Purity: 99.18% - 99.63%
• Color and Shape: White Powder
• Molecular weight: 482.19

PD 0325901

CAS: 391210-10-9

• Formula: C₁₆H₁₄F₃IN₂O₄
• Purity: ≥ 98.0%
• Color and Shape: White to off-white solid
• Molecular weight: 482.19

PD 0325901

CAS: 391210-10-9

• Formula: C₁₆H₁₄F₃IN₂O₄
• Molecular weight: 482.20

PD0325901

CAS: 391210-10-9

• Formula: C₁₆H₁₄F₃IN₂O₄
• Purity: 99.88% (lc-ms) (Typical Value in Batch COA)
• Color and Shape: white to off-white solid
• Molecular weight: 482.19g/mol

PD 0325901

CAS: 391210-10-9

A potent non ATP-competitive inhibitor of MAP/ERK kinase (MEK). Has anti-tumor activity in melanoma and …

• Formula: C₁₆H₁₄F₃IN₂O₄
• Purity: Min. 95%
• Molecular weight: 482.19 g/mol

rac-PD-325901-d5

CAS: 391210-10-9

• Formula: C₁₆D₅H₉F₃IN₂O₄
• Color and Shape: Neat
• Molecular weight: 487.224