CAS 391210-10-9: N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide

Description: N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide, with CAS number 391210-10-9, is a synthetic organic compound characterized by its complex molecular structure, which includes multiple functional groups such as amides, fluorine, and iodine substituents. This compound features a benzamide core, which is modified by the presence of difluoro and iodo groups, contributing to its potential biological activity. The dihydroxypropoxy moiety suggests that it may exhibit hydrophilic properties, enhancing its solubility in polar solvents. The presence of halogens, particularly fluorine and iodine, often influences the compound's reactivity and pharmacokinetic properties, making it of interest in medicinal chemistry. Such compounds are typically investigated for their potential therapeutic applications, including anti-cancer or anti-inflammatory activities. Additionally, the stereochemistry indicated by the (2R) configuration may play a crucial role in the compound's biological interactions and efficacy. Overall, this compound exemplifies the intricate design often found in drug development, where specific substitutions are made to optimize desired properties.

Formula: C₁₆H₁₄F₃IN₂O₄

InChI: InChI=1S/C16H14F3IN2O4/c17-11-3-2-10(16(25)22-26-7-9(24)6-23)15(14(11)19)21-13-4-1-8(20)5-12(13)18/h1-5,9,21,23-24H,6-7H2,(H,22,25)/t9-/m1/s1

InChI key: InChIKey=SUDAHWBOROXANE-SECBINFHSA-N

SMILES: O=C(NOCC(O)CO)C1=CC=C(F)C(F)=C1NC2=CC=C(I)C=C2F

Synonyms:

• Benzamide, N-[(2R)-2,3-dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-
• Mirdametinib
• N-(2,3-dihydroxypropoxy)-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide
• N-[((R)-2,3-Dihydroxypropyl)oxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide
• N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-(2-fluoro-4-iodoanilino)benzamide
• N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide
• Pd 0325901
• Pd 03525901
• Pd 325901
• Pd 901
• Pd325901

N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide

CAS: 391210-10-9

• Formula: C₁₆H₁₄F₃IN₂O₄
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 482.193

Mirdametinib

CAS: 391210-10-9

• Purity: 99.9%
• Molecular weight: 482.19g/mol

PD 0325901

CAS: 391210-10-9

• Formula: C₁₆H₁₄F₃IN₂O₄
• Purity: >97.0%(T)(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 482.20

PD 0325901

CAS: 391210-10-9

• Formula: C₁₆H₁₄F₃IN₂O₄
• Purity: ≥ 98.0%
• Color and Shape: White to off-white solid
• Molecular weight: 482.19

Mirdametinib

CAS: 391210-10-9

Mirdametinib (PD325901) is an MEK inhibitor (IC50=0.33 nM) with selective, non-ATP-competitive, and oral activity.

• Formula: C₁₆H₁₄F₃IN₂O₄
• Purity: 99.18% - 99.63%
• Color and Shape: White Powder
• Molecular weight: 482.19

PD0325901

CAS: 391210-10-9

• Formula: C₁₆H₁₄F₃IN₂O₄
• Purity: 99.88% (lc-ms) (Typical Value in Batch COA)
• Color and Shape: white to off-white solid
• Molecular weight: 482.19g/mol

PD 0325901

CAS: 391210-10-9

• Formula: C₁₆H₁₄F₃IN₂O₄
• Molecular weight: 482.20

PD 0325901

CAS: 391210-10-9

A potent non ATP-competitive inhibitor of MAP/ERK kinase (MEK). Has anti-tumor activity in melanoma and …

• Formula: C₁₆H₁₄F₃IN₂O₄
• Purity: Min. 95%
• Molecular weight: 482.19 g/mol

rac-PD-325901-d5

CAS: 391210-10-9

• Formula: C₁₆D₅H₉F₃IN₂O₄
• Color and Shape: Neat
• Molecular weight: 487.224