CAS 3913-67-5

N-Methyl-L-alanine

Description:

N-Methyl-L-alanine is a non-proteinogenic amino acid characterized by the presence of a methyl group attached to the nitrogen atom of the L-alanine structure. Its molecular formula is C4H9NO2, indicating it contains four carbon atoms, nine hydrogen atoms, one nitrogen atom, and two oxygen atoms. This compound is typically a white crystalline solid and is soluble in water due to the presence of its amino and carboxyl functional groups. N-Methyl-L-alanine is of interest in biochemical research, particularly in studies related to protein synthesis and metabolic pathways. It can act as a building block for peptides and may influence various physiological processes. Additionally, its methylation can affect the properties and functions of proteins, making it a subject of interest in the fields of medicinal chemistry and pharmacology. As with many amino acids, it is important to handle N-Methyl-L-alanine with care in laboratory settings, adhering to safety protocols to avoid any potential hazards.

Formula: C₄H₉NO₂

InChI: InChI=1S/C4H9NO2/c1-3(5-2)4(6)7/h3,5H,1-2H3,(H,6,7)/t3-/m0/s1

InChI key: InChIKey=GDFAOVXKHJXLEI-VKHMYHEASA-N

SMILES: [C@H](C(O)=O)(NC)C

Synonyms:

• (2S)-2-(Methylamino)propanoic acid
• (S)-2-(Methylamino)propanoic acid
• (S)-N-Methylalanine
• 2-(Methylamino)propanoic acid
• <span class="text-smallcaps">L</span>-Alanine, N-methyl-
• Alanine, N-methyl-, <span class="text-smallcaps">L</span>-
• N-Me-Ala-OH
• N-Methyl-<span class="text-smallcaps">L</span>-alanine
• N-Methyl-L-Aminopropanoic Acid
• N-Methylalanine
• N-α-Methyl-L-alanine
• α-(Methylamino)propionic acid
• Alanine, N-methyl-, L-
• N-Methyl-L-alanine

N-Me-Ala-OH

CAS: 3913-67-5

Bachem ID: 4002601.

Formula: C₄H₉NO₂

Purity: 99.6%

Color and Shape: White

Molecular weight: 103.12

Ref: 01-4002601

Alanine, N-methyl-

CAS: 3913-67-5

Formula: C₄H₉NO₂

Purity: 96%

Color and Shape: Solid

Molecular weight: 103.1198

Ref: IN-DA00I7Q5

N-Methyl-L-alanine

CAS: 3913-67-5

N-Methyl-L-alanine

Formula: C₄H₉NO₂

Purity: 97%

Color and Shape: white to off-white solid

Molecular weight: 103.12g/mol

Ref: 54-OR61451

N-Methyl-L-alanine

CAS: 3913-67-5

Formula: C₄H₉NO₂

Molecular weight: 103.12

Ref: 7W-GM1676

N-Methyl-L-alanine

CAS: 3913-67-5

Formula: C₄H₉NO₂

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 103.12

Ref: 3B-M2436

N-Methyl-L-Alanine

CAS: 3913-67-5

Formula: C₄H₉NO₂

Molecular weight: 103.12

Ref: 4Z-A-155064

N-Methyl-L-alanine

Controlled Product

CAS: 3913-67-5

Applications N-Methyl-L-alanine is a reactant used in the preparation of site-specific trastuzumab maytansinoid antibody-drug conjugates with improved therapeutic activity.
References Pillow, T.H., et. al.: J. Med. Chem., 57, 7890 (2014)

Formula: C₄H₉NO₂

Color and Shape: Neat

Molecular weight: 103.12

Ref: TR-M276565

N-Methyl-L-alanine

CAS: 3913-67-5

Formula: C₄H₉NO₂

Purity: 96%

Color and Shape: Solid

Molecular weight: 103.121

Ref: 10-F075289

N-Methyl-L-alanine-13CD3

Controlled Product

CAS: 3913-67-5

Applications N-Methyl-L-alanine-13CD3 is an intermediate used in the synthesis of Mertansine-13CD3 (M257802), which is the isotope labelled analog of Mertansine (M257800); a cytotoxic agent used as the cytotoxic component in antibody-drug conjugates.
References Erickson, H., et al.: Cancer Res., 66, 4426 (2006); Kellogg, B., et al.: Bioconjugate Chem., 22, 717 (2011)

Formula: CC₃D₃H₆NO₂

Color and Shape: Neat

Molecular weight: 107.131

Ref: TR-M276566