CAS 39133-31-8

(±)-Trimebutine

Description:

(±)-Trimebutine is a synthetic compound primarily used as an antispasmodic and analgesic agent, particularly in the treatment of gastrointestinal disorders. It functions as a selective agonist of the opioid receptors, which helps in modulating gut motility and alleviating pain associated with gastrointestinal spasms. The substance is characterized by its ability to relax smooth muscle tissue, making it effective in conditions such as irritable bowel syndrome and other functional gastrointestinal disorders. Chemically, (±)-Trimebutine is classified as a butyrophenone derivative and exhibits a chiral structure, which means it exists in two enantiomeric forms. Its pharmacological profile includes a low incidence of side effects, making it a preferred choice in clinical settings. The compound is typically administered orally and is well-absorbed in the gastrointestinal tract. Additionally, (±)-Trimebutine is recognized for its safety profile, although it should be used under medical supervision, especially in patients with specific health conditions or those taking other medications.

Formula: C₂₂H₂₉NO₅

InChI: InChI=1/C22H29NO5/c1-7-22(23(2)3,17-11-9-8-10-12-17)15-28-21(24)16-13-18(25-4)20(27-6)19(14-16)26-5/h8-14H,7,15H2,1-6H3

InChI key: InChIKey=LORDFXWUHHSAQU-UHFFFAOYSA-N

SMILES: C(COC(=O)C1=CC(OC)=C(OC)C(OC)=C1)(N(C)C)(CC)C2=CC=CC=C2

Synonyms:

• 2-(Dimethylamino)-2-phenylbutyl (-)-3,4,5-trimethoxybenzoate
• 3,4,5-Trimethoxy Benzoic Dimethyl Amido-2-Phenyl Butylester
• 3,4,5-Trimethoxybenzoic acid 2-(dimethylamino)-2-phenylbutyl ester
• Benzoic acid, 3,4,5-trimethoxy-, 2-(dimethylamino)-2-phenylbutyl ester
• Trimebutine
• Triton
• Triton (pharmaceutical)
• Trimebutine hydrochloride
• 3,4,5-TRIMETHOXYBENZOICACID2-(DIMETHYLAMINO)-2-PHENYLBUTYLESTER(TRIMEBUTINE)
• Benzoic acid, 3,4,5-trimethoxy-, 2-(dimethylamino)-2-phenylbutyl ester (9CI)
• 2'-PHENYL-2'-DIMETHYLAMINO-N-BUTYL-3',4',5'-TRIMETHOXYBENZOATE
• TrimebutineMeleate34140-59-5/Base
• TRIMEBUTINE3.4.5-TRIMETHOXYBENZOATE,-2'-PHENYL-2'-DIMETHYLAMINO-N-BUTYL
• TRIMEBUTIN
• 3,4,5-TRIMETHOXYBENZOATE,-2'-PHENYL-2'-DIMETHYLAMINO-N-BUTYL

Trimebutine

CAS: 39133-31-8

Formula: C₂₂H₂₉NO₅

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 387.48

Ref: 3B-T3049

Trimebutine

CAS: 39133-31-8

Color and Shape: Neat

Ref: 61-FOR0417.00

Trimebutine

CAS: 39133-31-8

Trimebutine

Purity: 98%

Molecular weight: 387.47g/mol

Ref: 54-OR1030243

Trimebutine

CAS: 39133-31-8

Trimebutine (Mebutin) is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu-opioid

Formula: C₂₂H₂₉NO₅

Purity: 99.49% - 99.86%

Color and Shape: Solid

Molecular weight: 387.47

Ref: TM-T0918

Trimebutine

CAS: 39133-31-8

Trimebutine

Purity: ≥98%

Molecular weight: 387.47g/mol

Ref: 54-BUP19225

Trimebutine

CAS: 39133-31-8

Formula: C₂₂H₂₉NO₅

Color and Shape: White To Off-White Solid

Molecular weight: 387.48

Ref: 4Z-T-1610

Trimebutine

Controlled Product

CAS: 39133-31-8

Formula: C₂₂H₂₉NO₅

Color and Shape: Neat

Molecular weight: 387.47

Ref: 86-MM0417.00

Trimebutine

CAS: 39133-31-8

Applications Trimebutine is an opioid receptor agonist and an antispasmodic agent (1,2). It is used to treat acute and chronic abdominal pain.
References (1) Delvaux, M., et al.: J. Int. Med. Res., 25, 225 (1997) (2) Lavit, M., et al.: Arzneim.-Forsch., 50, 640 (2000)

Formula: C₂₂H₂₉NO₅

Color and Shape: Off White Crystalline Powder

Molecular weight: 387.47

Ref: TR-T795565

Trimebutine

CAS: 39133-31-8

Formula: C₂₂H₂₉NO₅

Molecular weight: 387.50

Ref: ST-EA-CP-T6000