CAS 3916-78-7

6-chloropyridazine-3(2H)-thione

Description:

6-Chloropyridazine-3(2H)-thione is a heterocyclic compound characterized by its pyridazine ring, which is a six-membered aromatic ring containing two nitrogen atoms at positions 1 and 2. The presence of a chlorine atom at the 6-position and a thione functional group at the 3-position contributes to its unique chemical properties. This compound typically exhibits a yellow to brown color and is soluble in organic solvents. It may participate in various chemical reactions, including nucleophilic substitutions and condensation reactions, due to the reactivity of the thione group. The thione functionality can also engage in tautomeric shifts, interconverting between thione and thiol forms. 6-Chloropyridazine-3(2H)-thione has potential applications in medicinal chemistry and agrochemicals, serving as a scaffold for the development of biologically active compounds. Its specific reactivity and interactions can be influenced by the presence of the chlorine substituent, which can affect electronic distribution and steric hindrance within the molecule.

Formula: C₄H₃ClN₂S

InChI: InChI=1/C4H3ClN2S/c5-3-1-2-4(8)7-6-3/h1-2H,(H,7,8)

SMILES: c1cc(nnc1Cl)S

Synonyms:

• 3(2H)-Pyridazinethione, 6-chloro-
• 3-Pyridazinethiol, 6-Chloro-
• 6-Chloro-3(2H)-pyridazinethione
• 6-Chloro-3-pyridazinethiol
• T6Nmyj Cus Fg
• T6Nnj Csh Fg

6-Chloro-3(2H)-pyridazinethione

CAS: 3916-78-7

Formula: C₄H₃ClN₂S

Purity: 95%

Color and Shape: Solid

Molecular weight: 146.5980

Ref: IN-DA0037WR

6-Chloro-3(2H)-pyridazinethione

CAS: 3916-78-7

6-Chloro-3(2H)-pyridazinethione

Purity: 97%

Molecular weight: 146.6g/mol

Ref: 54-OR1043432

6-Chloropyridazine-3-thiol

CAS: 3916-78-7

6-Chloropyridazine-3-thiol is a potent inhibitor of platelet aggregation. This drug binds to the active site of the enzyme ADP-thrombin, thereby blocking the conversion of ADP to thrombin. 6-Chloropyridazine-3-thiol has been shown to have a high affinity for human liver microsomes, and is metabolized by conjugation with glutathione or glucuronide. 6CpT also inhibits the activation of factor V and factor VIII, which are involved in blood clotting. It is hypothesized that this inhibition may be due to its ability to bind to reactive chlorine atoms found on these proteins. 6-Chloropyridazine-3-thiol is a potent inhibitor of platelet aggregation, but it does not show any antiplatelet activity when used at low doses.

Formula: C₄H₃ClN₂S

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 146.6 g/mol

Ref: 3D-FC121917

6-Chloropyridazine-3(2H)-thione

CAS: 3916-78-7

Purity: 95%

Molecular weight: 146.5899963

Ref: 10-F620980