CAS 391860-73-4

Quinoline, 6-chloro-2-cyclopropyl-4-(trifluoromethyl)-

Description:

Quinoline, 6-chloro-2-cyclopropyl-4-(trifluoromethyl)-, identified by CAS number 391860-73-4, is a heterocyclic organic compound that features a quinoline backbone, which consists of a fused benzene and pyridine ring. This compound is characterized by the presence of a chlorine atom at the 6-position, a cyclopropyl group at the 2-position, and a trifluoromethyl group at the 4-position of the quinoline ring. The trifluoromethyl group is known for its electron-withdrawing properties, which can significantly influence the compound's reactivity and stability. The cyclopropyl group introduces strain and can affect the compound's conformational flexibility. Quinoline derivatives are often studied for their biological activities, including potential applications in pharmaceuticals and agrochemicals. The presence of halogens and other functional groups can enhance the compound's lipophilicity and influence its interaction with biological targets. Overall, this compound exemplifies the complexity and diversity of quinoline derivatives in organic chemistry.

Formula: C₁₃H₉ClF₃N

Efavirenz Related Compound C (6-chloro-2-cyclopropyl-4-(trifluoromethyl)quinoline)

CAS: 391860-73-4

Compounds (excluding drugs and pesticides) containing a quinoline or isoquinoline ring-system (whether or not hydrogenated) not further fused, nesoi

Formula: C₁₃H₉ClF₃N

Color and Shape: Off-White Powder

Molecular weight: 271.03756

Ref: 45-1234136

Efavirenz Related Compound C (20 mg) (6-chloro-2-cyclopropyl-4-(trifluoromethyl)quinoline)

CAS: 391860-73-4

Formula: C₁₃H₉ClF₃N

Purity: 97%

Color and Shape: Solid

Molecular weight: 271.6655

Ref: IN-DA00C79N

6-Chloro-2-cyclopropyl-4-(trifluoromethyl)quinoline

CAS: 391860-73-4

6-Chloro-2-cyclopropyl-4-(trifluoromethyl)quinoline

Purity: 97%

Molecular weight: 271.67g/mol

Ref: 54-PC1006775

Efavirenz Related Compound C

CAS: 391860-73-4

Formula: C₁₃H₉ClF₃N

Color and Shape: Yellow Solid

Molecular weight: 271.67

Ref: 4Z-E-075

Efavirenz USP Related Compound C

Controlled Product

CAS: 391860-73-4

Formula: C₁₃H₉ClF₃N

Color and Shape: Neat

Molecular weight: 271.67

Ref: 86-MM0919.05

6-Chloro-2-cyclopropyl-4-(trifluoromethyl)-quinoline

Controlled Product

CAS: 391860-73-4

Impurity Efavirenz USP Related Compound C/ Efavirenz Quinoline Impurity
Applications 6-Chloro-2-cyclopropyl-4-(trifluoromethyl)-quinoline is an impurity of Efavirenz (E425000), a nonnucleoside HIV-1 reverse transcriptase inhibitor and antiviral agent.
References Young, S.D., et al.: Antimicrob. Ag. Chemother., 39, 2602 (1995), Jiang, B., et al.: Euro. J. Org. Chem., 16, 2693 (2008); Ribeiro, J.A., et al.: J. Pharma. Biomed. Anal., 43, 298 (2007);

Formula: C₁₃H₉ClF₃N

Color and Shape: Neat

Molecular weight: 271.67

Ref: TR-C365545