CAS 392-04-1

Benzoic acid, 4-fluoro-2-hydroxy-, methyl ester

Description:

Benzoic acid, 4-fluoro-2-hydroxy-, methyl ester, commonly referred to as methyl 4-fluoro-2-hydroxybenzoate, is an organic compound characterized by its ester functional group derived from benzoic acid. It features a fluorine atom and a hydroxyl group positioned on the benzene ring, which contributes to its unique chemical properties. This compound is typically a colorless to pale yellow liquid or solid, depending on its purity and temperature. It is soluble in organic solvents and exhibits moderate solubility in water due to the presence of the hydroxyl group. The presence of the fluorine atom can influence its reactivity and polarity, making it useful in various chemical syntheses and applications. Methyl 4-fluoro-2-hydroxybenzoate is often utilized in the pharmaceutical industry and as an intermediate in organic synthesis. Safety data indicates that it should be handled with care, as it may pose health risks if ingested or inhaled. Proper safety protocols should be followed when working with this compound in laboratory settings.

Formula: C₈H₇FO₃

InChI: InChI=1S/C8H7FO3/c1-12-8(11)6-3-2-5(9)4-7(6)10/h2-4,10H,1H3

InChI key: InChIKey=WPWUDDDJTIZBGL-UHFFFAOYSA-N

SMILES: C(OC)(=O)C1=C(O)C=C(F)C=C1

Synonyms:

• 4-Fluoro-2-hydroxybenzoic acid methyl ester
• 4-Fluoro-6-hydroxy-benzoic acid methyl ester
• 4-Fluorosalicylic acid methyl ester
• Benzoic acid, 4-fluoro-2-hydroxy-, methyl ester
• Methyl 4-fluorosalicylate
• Salicylic acid, 4-fluoro-, methyl ester
• Methyl 4-fluoro-2-hydroxybenzoate
• Methyl 4-fluoro-2-hydroxybenzoate

Methyl 4-fluoro-2-hydroxybenzoate

CAS: 392-04-1

Formula: C₈H₇FO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 170.1378

Ref: IN-DA00357M

Methyl 4-fluoro-2-hydroxybenzoate

CAS: 392-04-1

Methyl 4-fluoro-2-hydroxybenzoate

Formula: C₈H₇FO₃

Purity: 98%

Color and Shape: off white to light yellow/brown crystalline solid

Molecular weight: 170.14g/mol

Ref: 54-PC4187

4-Fluoro-2-hydroxybenzoic acid methyl ester

CAS: 392-04-1

4-Fluoro-2-hydroxybenzoic acid methyl ester is a chemical compound that is used as a synthetic intermediate in the synthesis of drugs. 4-Fluoro-2-hydroxybenzoic acid methyl ester can be prepared by reductive amination of an acyl chloride with an amine, followed by reaction with methanol. This chemical intermediate is used in the synthesis of the BCL-2 inhibitor venetoclax, which inhibits cell growth and induces apoptosis in lymphoma cells. 4-Fluoro-2-hydroxybenzoic acid methyl ester also has been shown to inhibit the activity of amidating enzymes and transferases, suggesting it may have potential as an anti-inflammatory drug.

Formula: C₈H₇FO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 170.14 g/mol

Ref: 3D-FF67622

Methyl 4-fluoro-2-hydroxybenzoate

CAS: 392-04-1

Formula: C₈H₇FO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 170.139

Ref: 10-F079096