CAS 392-13-2

5-Fluoro-3-methyl-1H-indole

Description:

5-Fluoro-3-methyl-1H-indole is an organic compound belonging to the indole family, characterized by a bicyclic structure that consists of a fused benzene and pyrrole ring. This compound features a fluorine atom at the 5-position and a methyl group at the 3-position of the indole ring, which influences its chemical reactivity and biological properties. It is typically a solid at room temperature and is known for its aromatic characteristics, contributing to its stability and potential applications in pharmaceuticals and agrochemicals. The presence of the fluorine atom can enhance lipophilicity and metabolic stability, making it a valuable scaffold in drug design. Additionally, 5-Fluoro-3-methyl-1H-indole may exhibit interesting biological activities, including antimicrobial and anticancer properties, although specific activities can vary based on structural modifications and the biological context. As with many indole derivatives, it may also participate in various chemical reactions, such as electrophilic substitutions, due to the electron-rich nature of the indole nitrogen.

Formula: C₉H₈FN

InChI: InChI=1S/C9H8FN/c1-6-5-11-9-3-2-7(10)4-8(6)9/h2-5,11H,1H3

InChI key: InChIKey=CSDHAGJNOQIBHZ-UHFFFAOYSA-N

SMILES: CC=1C=2C(=CC=C(F)C2)NC1

Synonyms:

• 1H-Indole, 5-fluoro-3-methyl-
• 5-fluoro-3-methyl-1H-indole
• Indole, 5-fluoro-3-methyl-
• 5-Fluoro-3-Methylindole
• 5-Fluoro-3-methylindole

1H-Indole, 5-fluoro-3-methyl-

CAS: 392-13-2

Formula: C₉H₈FN

Purity: 97%

Color and Shape: Solid

Molecular weight: 149.1649

Ref: IN-DA00I7QJ

5-Fluoro-3-methylindole

CAS: 392-13-2

Ref: 7W-GK8030

5-Fluoro-3-methylindole

CAS: 392-13-2

Formula: C₉H₈FN

Purity: >98.0%(GC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 149.17

Ref: 3B-F1053

5-Fluoro-3-methyl-1H-indole

CAS: 392-13-2

5-Fluoro-3-methyl-1H-indole

Purity: ≥95%

Color and Shape: Off-White Powder

Molecular weight: 149.16g/mol

Ref: 54-PC3027

5-Fluoro-3-methylindole

CAS: 392-13-2

5-Fluoro-3-methylindole is a reactive compound that is not soluble in water. It has a molecular weight of 288.5 and an ionization potential of 7.8 eV. 5-Fluoro-3-methylindole can act as a potent antagonist by binding to the pharmacophore, which is the three hydrogen bonding sites on the benzodiazepine receptor. This drug has been shown to be reactive with halides, nitro, and magnesium, as well as with some endogenous compounds such as nitroarenes and amides. 5-Fluoro-3-methylindole also reacts with fluorescence ligands and transfer agents.

Formula: C₉H₈FN

Purity: Min. 95%

Molecular weight: 149.16 g/mol

Ref: 3D-FF52320

5-Fluoro-3-methylindole

CAS: 392-13-2

5-Fluoro-3-methylindole is a versatile building block and reagent for research chemicals. It is also a useful intermediate in the synthesis of other compounds, such as pharmaceuticals, pesticides, and fragrances. 5-Fluoro-3-methylindole has been shown to be useful for the preparation of complex compounds with high quality and high purity. This chemical is used as a reaction component or scaffold in organic synthesis.

Formula: C₉H₈FN

Molecular weight: 149.17 g/mol

Ref: 3D-F-5915

5-Fluoro-3-methylindole

CAS: 392-13-2

Formula: C₉H₈FN

Purity: 97%

Color and Shape: Liquid, No data available.

Molecular weight: 149.168

Ref: 10-F092387

5-Fluoro-3-methylindole

Controlled Product

CAS: 392-13-2

Applications 5-Fluoro-3-methylindole is used to study its ionization potential and the origin of nonexponential tryptophan fluorescnece decay in proteins.
References Liu, T., et al.: J. Am. Chem. Soc., 128, 4104 (2005);

Formula: C₉H₈FN

Color and Shape: Neat

Molecular weight: 149.165

Ref: TR-F597990