CAS 39227-28-6

1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin

Description:

1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin (HCDD) is a highly chlorinated organic compound belonging to the class of dioxins, which are known for their environmental persistence and toxicity. It is characterized by a structure that includes two benzene rings connected by two oxygen atoms, with six chlorine atoms substituted at specific positions on the rings. HCDD is a byproduct of various industrial processes, including the production of herbicides and the combustion of organic materials. It is lipophilic, meaning it tends to accumulate in fatty tissues of living organisms, leading to bioaccumulation and potential biomagnification in food chains. The compound is classified as a persistent organic pollutant (POP) due to its stability and resistance to degradation. Exposure to HCDD has been associated with a range of adverse health effects, including immune system suppression, reproductive and developmental issues, and increased risk of certain cancers. Regulatory agencies monitor and control its presence in the environment due to its hazardous nature and potential impact on human health and ecosystems.

Formula: C₁₂H₂Cl₆O₂

InChI: InChI=1/C12H2Cl6O2/c13-3-1-5-6(2-4(3)14)20-12-10(18)8(16)7(15)9(17)11(12)19-5/h1-2H

InChI key: InChIKey=WCYYQNSQJHPVMG-UHFFFAOYSA-N

SMILES: ClC1=C2C(OC=3C(O2)=CC(Cl)=C(Cl)C3)=C(Cl)C(Cl)=C1Cl

Synonyms:

• 1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin
• 1,2,3,4,7,8-Hexachlorodibenzo[1,4]dioxin
• 1,2,3,4,7,8-Hexachlorodibenzo[b,e][1,4]dioxin
• 1,2,3,4,7,8-Hexachlorodibenzodioxin
• 1,2,3,4,7,8-HxCDD
• D 66
• Pcdd 66
• 1,2,3,4,7,8-Hexachloro-dibenzo[b,e][1,4]dioxin
• 1,2,3,4,7,8-Hexachlorooxanthrene
• dibenzo[b,e][1,4]dioxin, 1,2,3,4,7,8-hexachloro-
• Dibenzo[b,e][1,4]dioxin, 1,2,3,4,7,8-hexachloro-
• Hexachlorodibenzodioxin, 1,2,3,4,7,8-: (HexaCDD, 1,2,3,4,7,8-)
• d66
• Hcdd
• Dibenzo-p-dioxin, hexachloro-
• Hexachlorodibenzo-p-dioxin
• 1,2,3,4,7,8-hexachloro-dibenzo-p-dioxi
• 1,2,3,4,7,8-HCDD

1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin

CAS: 39227-28-6

1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin is a polychlorinated dibenzodioxin (PCDD) congener. At the highest dose (10,000 μg/kg), it can cause hepatic pallor (fatty liver), gastrointestinal bleeding, and early mortality in H/W and A strain rats. Additionally, 1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin induces liver sinusoidal dilatation and can lead to severe purpura in B strain rats.

Formula: C₁₂H₂Cl₆O₂

Color and Shape: Solid

Molecular weight: 390.86

Ref: TM-T203271

1,2,3,4,7,8-Hexachlorodibenzodioxin

CAS: 39227-28-6

Formula: C₁₂H₂Cl₆O₂

Molecular weight: 390.85

Ref: 4Z-D-126008

1,2,3,4,7,8-Hexachlorodibenzodioxin (>90%)

CAS: 39227-28-6

Applications A toxic polychlorinated dibenzo-p-dioxin detected in domestic meat and poultry.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Feil, V., et al.: J. Agric. Food Chem., 48, 6163 (2000), Huwe, J., et al.: Food Addit. Contam., 21, 182 (2004), Llobet, J., et al.: Toxicol. Lett., 178, 117 (2008),

Formula: C₁₂H₂Cl₆O₂

Purity: >90%

Color and Shape: Neat

Molecular weight: 390.86

Ref: TR-H290780

1,2,3,4,7,8-Hexachlorodibenzodioxin

CAS: 39227-28-6

Hexachlorodibenzodioxin is a chemical that has been classified as a probable human carcinogen by the International Agency for Research on Cancer. The chronic effects of hexachlorodibenzodioxin are not well understood, but it has been shown to have short-term effects on body weight and IGF-I levels in Sprague-Dawley rats. Hexachlorodibenzodioxin is also an inducer of cancer in humans and animals. It has been used as a standard for analytical methods in clinical responses, growth factors, and cancer.

Formula: C₁₂H₂Cl₆O₂

Purity: Min. 95%

Molecular weight: 390.86 g/mol

Ref: 3D-FH23771