CAS 39243-02-2

8-Bromo-1-methyl-6-(2-pyridinyl)-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine

Description:

8-Bromo-1-methyl-6-(2-pyridinyl)-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine is a chemical compound characterized by its complex structure, which includes a benzodiazepine core fused with a triazole ring. This compound features a bromine atom at the 8-position and a methyl group at the 1-position, contributing to its unique reactivity and potential biological activity. The presence of a pyridine ring at the 6-position enhances its lipophilicity and may influence its interaction with biological targets. Typically, compounds of this class are studied for their pharmacological properties, including anxiolytic, anticonvulsant, and sedative effects. The molecular structure allows for various interactions with neurotransmitter systems, particularly those involving GABA receptors. Additionally, the compound's solubility, stability, and reactivity can be influenced by the substituents on the benzodiazepine and triazole rings. As with many synthetic organic compounds, safety and handling precautions are essential due to potential toxicity and environmental impact.

Formula: C₁₆H₁₂BrN₅

InChI: InChI=1S/C16H12BrN5/c1-10-20-21-15-9-19-16(13-4-2-3-7-18-13)12-8-11(17)5-6-14(12)22(10)15/h2-8H,9H2,1H3

InChI key: InChIKey=BGRWSFIQQPVEML-UHFFFAOYSA-N

SMILES: CC=1N2C=3C(C(=NCC2=NN1)C4=CC=CC=N4)=CC(Br)=CC3

Synonyms:

• 8-Bromo-1-methyl-6-(2-pyridinyl)-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
• Pyrazolam
• 4H-[1,2,4]Triazolo[4,3-a][1,4]benzodiazepine, 8-bromo-1-methyl-6-(2-pyridinyl)-
• Pyrazolam solution
• 8-Bromo-1-methyl-6-(pyridin-2-yl)-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine
• 8-Bromo-1-methyl-6-(2-pyridinyl)-4H-[1,2,4]triazolo[4,3-a][1,4]be nzodiazepine
• formaty

Pyrazolam 1.0 mg/ml in Methanol

Controlled Product

CAS: 39243-02-2

Color and Shape: Single Solution

Ref: 61-AMP1441.00-01

Pyrazolam

Controlled Product

CAS: 39243-02-2

Color and Shape: Neat

Ref: 61-FOR1441.00

Pyrazolam

CAS: 39243-02-2

Pyrazolam is a psychoactive benzodiazepine compound serving as a central nervous system depressant. [Pyrazolam] can lead to psychomotor impairment.

Formula: C₁₆H₁₂BrN₅

Color and Shape: Solid

Molecular weight: 354.2

Ref: TM-T203686

Pyrazolam

Controlled Product

CAS: 39243-02-2

Applications Pyrazolam is a benzodiazepine with an elimination half-life of about 17 hours and no detectable metabolites in human serum and urine; thus pyrazolam may go undetected without instrumental analytical techniques.
References Moosmann, B., et. al.: Forensic Toxicol., 31, 263 (2013)

Formula: C₁₆H₁₂BrN₅

Color and Shape: Neat

Molecular weight: 354.20

Ref: TR-P841770

Pyrazolam-d3

Controlled Product

CAS: 39243-02-2

Formula: C₁₆H₉D₃BrN₅

Color and Shape: Neat

Molecular weight: 357.22

Ref: TR-P841773

Pyrazolam

Controlled Product

CAS: 39243-02-2

8-Bromo-1-methyl-6-(pyridin-2-yl)-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine (8BrMPT) is a magnetic resonance imaging (MRI) contrast agent. It has been shown to be effective in the treatment of epilepsy and other neurological disorders. 8BrMPT is also an immunochemical reagent for the detection of liver enzymes and human serum albumin. 8BrMPT has been shown to have pharmacokinetic properties that are similar to those of gadolinium chelates, with a half life of about 2 hours.

Formula: C₁₆H₁₂BrN₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 354.2 g/mol

Ref: 3D-FB59119

8-BROMO-1-METHYL-6-(PYRIDIN-2-YL)-4H-BENZO[F][1,2,4]TRIAZOLO[4,3-A][1,4]D+

CAS: 39243-02-2

Formula: C₁₆H₁₂BrN₅

Purity: 98%

Molecular weight: 354.2040

Ref: IN-DA01AT07