CAS 3930-20-9
:Sotalol
Description:
Sotalol is a synthetic compound primarily used as an antiarrhythmic medication, particularly for the treatment of ventricular arrhythmias and atrial fibrillation. It belongs to the class III antiarrhythmics and functions by prolonging the cardiac action potential and refractory period, thereby stabilizing heart rhythm. The chemical formula of Sotalol is C12H20N2O3S, and it features a sulfonamide group, which contributes to its pharmacological properties. Sotalol is known for its beta-blocking activity, which helps reduce heart rate and myocardial oxygen demand. It is typically administered orally and has a relatively long half-life, allowing for once or twice daily dosing. The substance is also characterized by its solubility in water, making it suitable for various formulations. Side effects may include bradycardia, fatigue, and potential for QT interval prolongation, necessitating monitoring during treatment. Overall, Sotalol is a crucial medication in managing specific cardiac conditions, with a well-established profile in clinical use.
Formula:C12H20N2O3S
InChI:InChI=1S/C12H20N2O3S/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17/h4-7,9,12-15H,8H2,1-3H3
InChI key:InChIKey=ZBMZVLHSJCTVON-UHFFFAOYSA-N
SMILES:C(CNC(C)C)(O)C1=CC=C(NS(C)(=O)=O)C=C1
Synonyms:- Methanesulfonamide, N-[4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]-
- Methanesulfonanilide, 4′-[1-hydroxy-2-(isopropylamino)ethyl]-
- N-[4-[1-Hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]methanesulfonamide
- 4′-[1-Hydroxy-2-(isopropylamino)ethyl]methanesulfonanilide
- Sotalol
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