CAS 3936-02-5

Dexamethasone sodium m-sulfobenzoate

Description:

Dexamethasone sodium m-sulfobenzoate is a synthetic corticosteroid and a derivative of dexamethasone, primarily used for its anti-inflammatory and immunosuppressive properties. It is characterized by its sodium salt form, which enhances its solubility in aqueous solutions, making it suitable for parenteral administration. The compound exhibits a high affinity for glucocorticoid receptors, leading to a range of biological effects, including the modulation of immune responses and the reduction of inflammation. Its chemical structure includes a steroid backbone with a sulfonate group, which contributes to its pharmacokinetic properties. Dexamethasone sodium m-sulfobenzoate is often utilized in various medical applications, including the treatment of allergic reactions, autoimmune disorders, and certain types of cancer. Additionally, it may be employed in veterinary medicine. As with other corticosteroids, its use can be associated with side effects, particularly with long-term administration, necessitating careful monitoring of patients. Overall, this compound represents a valuable therapeutic agent in the management of various inflammatory and immune-mediated conditions.

Formula: C₂₉H₃₃FO₉S·Na

InChI: InChI=1S/C29H33FO9S.Na/c1-16-11-22-21-8-7-18-13-19(31)9-10-26(18,2)28(21,30)23(32)14-27(22,3)29(16,35)24(33)15-39-25(34)17-5-4-6-20(12-17)40(36,37)38;/h4-6,9-10,12-13,16,21-23,32,35H,7-8,11,14-15H2,1-3H3,(H,36,37,38);/t16-,21+,22+,23+,26+,27+,28+,29+;/m1./s1

InChI key: InChIKey=QPTXTASNUUATEQ-RDWMNNCQSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@](F)([C@]4(C)C(CC3)=CC(=O)C=C4)[C@@H](O)C1)[H])(C[C@@H](C)[C@@]2(C(COC(=O)C5=CC(S(=O)(=O)O)=CC=C5)=O)O)[H].[Na]

Synonyms:

• 21-(3-Sulfobenzoyloxy)dexamethasone sodium salt
• Dexamethason 21-(3-sulfobenzoat)natrium
• Dexamethasone 21-sodium-m-sulfobenzoate
• Dexamethasone m-sulfobenzoate sodium
• Dexamethasone metasulfobenzoate sodium
• Dexamethasone sodium-m-sulfobenzoate
• Dexamethasone sulfobenzoate sodium
• Dexamethasone-21-sulphobenzoate sodium
• Dexamethazone metasulfobenzoate sodium
• Dexapos
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-((3-sulfobenzoyl)oxy)-, monosodium salt, (11beta,16alpha)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-[(3-sulfobenzoyl)oxy]-, sodium salt (1:1)
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11-beta,17,21-trihydroxy-16-alpha-methyl-, 21-m-sulfobenzoate, monosodium salt
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 21-(m-sulfobenzoate), monosodium salt
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 21-m-sulfobenzoate, sodium salt
• Sisotek
• Sodium 3-({[(11Beta,16Alpha)-9-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl]Oxy}Carbonyl)Benzenesulfonate
• Sodium dexamethasone-m-sulfobenzoate

Dexamethasone Sodium Sulfobenzoate

Controlled Product

CAS: 3936-02-5

Formula: C₂₉H₃₀FNaO₉S

Color and Shape: Neat

Molecular weight: 582.62

Ref: 86-MM0861.00

Desoximetasone Impurity 17 (Dexamethasone Sodium Metasulphobenzoate)

CAS: 3936-02-5

Formula: C₂₉H₃₂FO₉S·Na

Molecular weight: 575.62 22.99

Ref: 4Z-D-113028

Dexamethasone Sodium Sulfobenzoate

Controlled Product

CAS: 3936-02-5

Applications Dexamethasone Sodium Sulfobenzoate is related to Dexamethasone (D298800) a steroid that regulates T cell survival, growth, and differentiation.
References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995); Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999); Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999);

Formula: C₂₉H₃₂FO₉S·Na

Color and Shape: Neat

Molecular weight: 598.61

Ref: TR-D118963

Dexamethasone Sodium Metasulfobenzoate

CAS: 3936-02-5

Formula: C₂₉H₃₂FO₉SNa

Molecular weight: 575.62 : 23.0

Ref: ST-EA-CP-D17029

Dexamethasone sodium metasulfobenzoate

CAS: 3936-02-5

Dexamethasone sodium metasulfobenzoate is a steroid that modulates the immune system. It is used to treat bacterial infections and as an anti-inflammatory agent in the treatment of rheumatoid arthritis, post-operative inflammation, and other conditions. Dexamethasone inhibits the production of cytokines, such as tumor necrosis factor-α (TNF-α), by white blood cells. The molecule also has antibacterial properties and has been shown to be effective against HIV infection. Dexamethasone may be administered orally or intravenously. The drug's pharmacodynamics are dose dependent, with higher doses being associated with greater modulation of the immune response. The recommended dosage for adults is 0.6 mg/kg/day in divided doses every 6 hours for 7 days; for children it is 0.2 mg/kg/day in divided doses every 6 hours for 14 days.

Formula: C₂₉H₃₃FO₉S•Na

Purity: Min. 95%

Molecular weight: 599.62 g/mol

Ref: 3D-FD171219