CAS 39379-15-2

Neurotensin

Description:

Neurotensin is a neuropeptide that plays a significant role in various physiological processes, including the modulation of pain, regulation of body temperature, and influence on gastrointestinal function. It is composed of 13 amino acids and is synthesized primarily in the central nervous system and the gastrointestinal tract. Neurotensin acts as a neurotransmitter and neuromodulator, binding to specific receptors, notably the neurotensin receptor 1 (NTS1), which is involved in signaling pathways that affect neuronal excitability and neurotransmitter release. This peptide is also implicated in the regulation of dopaminergic activity, which can influence mood and behavior. In addition to its central nervous system functions, neurotensin has been shown to have effects on the cardiovascular system and may play a role in metabolic processes. Its CAS number, 39379-15-2, is used for identification in chemical databases. Overall, neurotensin is a crucial molecule in neurobiology and has potential implications in understanding various neurological and metabolic disorders.

Formula: C₇₈H₁₂₁N₂₁O₂₀

InChI: InChI=1/C78H121N21O20/c1-7-43(6)63(73(115)96-57(76(118)119)37-42(4)5)97-70(112)55(39-45-21-25-47(101)26-22-45)95-72(114)59-18-13-35-99(59)75(117)52(16-11-33-86-78(83)84)90-64(106)48(15-10-32-85-77(81)82)89-71(113)58-17-12-34-98(58)74(116)51(14-8-9-31-79)91-69(111)56(40-60(80)102)94-66(108)50(28-30-62(104)105)88-68(110)54(38-44-19-23-46(100)24-20-44)93-67(109)53(36-41(2)3)92-65(107)49-27-29-61(103)87-49/h19-26,41-43,48-59,63,100-101H,7-18,27-40,79H2,1-6H3,(H2,80,102)(H,87,103)(H,88,110)(H,89,113)(H,90,106)(H,91,111)(H,92,107)(H,93,109)(H,94,108)(H,95,114)(H,96,115)(H,97,112)(H,104,105)(H,118,119)(H4,81,82,85)(H4,83,84,86)

SMILES: CCC(C)C(C(=NC(CC(C)C)C(=O)O)O)N=C(C(Cc1ccc(cc1)O)N=C(C1CCCN1C(=O)C(CCCNC(=N)N)N=C(C(CCCNC(=N)N)N=C(C1CCCN1C(=O)C(CCCCN)N=C(C(CC(=N)O)N=C(C(CCC(=O)O)N=C(C(Cc1ccc(cc1)O)N=C(C(CC(C)C)N=C(C1CCC(=N1)O)O)O)O)O)O)O)O)O)O

Synonyms:

• 5-Oxoprolylleucyltyrosyl-Α-Glutamylasparaginyllysylprolylarginylarginylprolyltyrosylisoleucylleucine
• Pyr-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH
• Neurotensin
• MeSH ID: D009496
• NEUROTENSIN, BOVINE
• PYROGLU-LEU-TYR-GLU-ASN-LYS-PRO-ARG-ARG-PRO-TRP-ILE-LEU OH
• Neurotensin,PYR-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu,Pyr-LYENKPRRPYIL?, >97%
• PYROGLU-LEU-TYR-GLU-ASN-LYS-PRO-ARG-ARG-PRO-TYR-ILE-LEU
• PYR-LYENKPRRPYIL
• M.W. 1672.92 C78H121N21O20
• GLP-LEU-TYR-GLU-ASN-LYS-PRO-ARG-ARG-PRO-TYR-ILE-LEU
• PGLU-LEU-TYR-GLU-ASN-LYS-PRO-ARG-ARG-PRO-TYR-ILE-LEU
• NEUROTENSIN (1-13)
• PYR-LEU-TYR-GLU-ASN-LYS-PRO-ARG-ARG-PRO-TYR-ILE-LEU 2ACOH 6H2O
• NEUROTENSIN (HUMAN, BOVINE, CANINE)
• NEUROTENSIN (HUMAN, BOVINE, CANINE) 2ACOH 6H2O

Neurotensin, Guinea pig

CAS: 39379-15-2

For cellular and molecular biology applications

Formula: C₇₆H₁₁₉N₂₁O₂₁

Molecular weight: 1662.91

Ref: 02-J66243

Neurotensin

CAS: 39379-15-2

Neurotensin, a 13 amino acid peptide, regulates LH and prolactin, interacts with dopamine system.

Formula: C₇₈H₁₂₁N₂₁O₂₀

Purity: >99.99%

Color and Shape: Solid

Molecular weight: 1672.92

Ref: TM-TP1310

Neurotensin

CAS: 39379-15-2

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Formula: C₇₈H₁₂₁N₂₁O₂₀

Molecular weight: 1,672.96 g/mol

Ref: 3D-PP50553

Neurotensin

CAS: 39379-15-2

Neurotensin is a peptide with a basic structure that belongs to the family of neurotensin-like peptides. It is found in the brain and gastrointestinal tract. Neurotensin has been shown to inhibit the growth of squamous cell carcinoma cells and increase cytosolic calcium in HL-60 cells, which may be due to its ability to induce apoptosis. Neurotensin also has been shown to bind guanine nucleotide binding proteins (G proteins) and interfere with the polymerase chain reaction (PCR). The signal peptide sequence is cleaved during protein synthesis, which is followed by a series of enzymatic reactions that produce a mature neurotensin peptide.

Formula: C₇₈H₁₂₁N₂₁O₂₀

Purity: Min. 95%

Molecular weight: 1,672.92 g/mol

Ref: 3D-FN73513