CAS 39391-39-4

Nocardicin A

Description:

Nocardicin A is a naturally occurring antibiotic that belongs to the class of compounds known as beta-lactams, specifically a type of cephalosporin. It is produced by the bacterium Nocardia species and exhibits potent antibacterial activity, particularly against Gram-positive bacteria. The structure of Nocardicin A features a beta-lactam ring, which is crucial for its mechanism of action, as it inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. This action ultimately leads to cell lysis and death of the bacteria. Nocardicin A is characterized by its unique side chains, which contribute to its stability and efficacy against resistant strains. Additionally, it has shown potential in treating infections caused by multidrug-resistant organisms. Its pharmacological properties, including its spectrum of activity and potential side effects, are subjects of ongoing research, particularly in the context of antibiotic resistance. Overall, Nocardicin A represents an important compound in the field of medicinal chemistry and antibiotic development.

Formula: C₂₃H₂₄N₄O₉

InChI: InChI=1/C23H24N4O9/c24-16(22(31)32)9-10-36-15-7-3-12(4-8-15)18(26-35)20(29)25-17-11-27(21(17)30)19(23(33)34)13-1-5-14(28)6-2-13/h1-8,16-17,19,28,35H,9-11,24H2,(H,25,29)(H,31,32)(H,33,34)/b26-18+/t16-,17+,19-/m1/s1

InChI key: InChIKey=CTNZOGJNVIFEBA-UPSUJEDGSA-N

SMILES: [C@@H](C(O)=O)(N1C(=O)[C@@H](NC(/C(=N\O)/C2=CC=C(OCC[C@H](C(O)=O)N)C=C2)=O)C1)C3=CC=C(O)C=C3

Synonyms:

• (αR,3S)-3-[[(2Z)-2-[4-[(3R)-3-Amino-3-carboxypropoxy]phenyl]-2-(hydroxyimino)acetyl]amino]-α-(4-hydroxyphenyl)-2-oxo-1-azetidineacetic acid
• 1-Azetidineacetic acid, 3-[[(2Z)-2-[4-[(3R)-3-amino-3-carboxypropoxy]phenyl]-2-(hydroxyimino)acetyl]amino]-α-(4-hydroxyphenyl)-2-oxo-, (αR,3S)-
• 1-Azetidineacetic acid, 3-[[(2Z)-[4-[(3R)-3-amino-3-carboxypropoxy]phenyl](hydroxyimino)acetyl]amino]-α-(4-hydroxyphenyl)-2-oxo-, (αR,3S)-
• 1-Azetidineacetic acid, 3-[[[4-(3-amino-3-carboxypropoxy)phenyl](hydroxyimino)acetyl]amino]-α-(4-hydroxyphenyl)-2-oxo-, [3S-[1(S*),3R*[Z(S*)]]]-
• Antibiotic FR 1923
• Nocardicin A
• [3S-[1(S*),3R*[E(S*)]]]-3-[[[4-(3-Amino-3-carboxypropoxy)phenyl](hydroxyimino)acetyl]amino]-a-(4-hydroxyphenyl)-2-oxo-1-azetidineacetic Acid
• (3S,αR)-3-[[[4-[(R)-3-Amino-3-carboxypropoxy]phenyl]-[(Z)-hydroxyimino]acetyl]amino]-α-(4-hydroxyphenyl)-2-oxo-1-azetidineacetic acid
• (3S,αR)-3β-[[[4-[(3R)-3-Amino-3-carboxypropoxy]phenyl][(Z)-hydroxyimino]acetyl]amino]-α-(4-hydroxyphenyl)-2-oxo-1-azetidineacetic acid
• FR-1923
• FR-1923C

Nocardicin A

CAS: 39391-39-4

Nocardicin A, a moderate antibiotic agent, shows inhibitory for a wild spectrum of gram-negative bacteria.

Formula: C₂₃H₂₄N₄O₉

Purity: 98%

Color and Shape: Solid

Molecular weight: 500.46

Ref: TM-T25876