CAS 394-28-5

2-Bromo-5-fluorobenzoic acid

Description:

2-Bromo-5-fluorobenzoic acid is an aromatic carboxylic acid characterized by the presence of both bromine and fluorine substituents on the benzene ring. Specifically, the bromine atom is located at the second position and the fluorine atom at the fifth position relative to the carboxylic acid group. This compound typically appears as a white to off-white solid and is known for its moderate solubility in organic solvents, while being less soluble in water due to the hydrophobic nature of the aromatic ring. It exhibits acidic properties, allowing it to participate in various chemical reactions, including esterification and nucleophilic substitution. The presence of halogens can influence its reactivity and stability, making it useful in synthetic organic chemistry, particularly in the development of pharmaceuticals and agrochemicals. Additionally, 2-Bromo-5-fluorobenzoic acid can serve as a building block for more complex molecules, showcasing its versatility in chemical synthesis. Safety precautions should be observed when handling this compound, as it may pose health risks if ingested or inhaled.

Formula: C₇H₄BrFO₂

InChI: InChI=1/C7H4BrFO2/c8-6-2-1-4(9)3-5(6)7(10)11/h1-3H,(H,10,11)/p-1

InChI key: InChIKey=OQBMJMJZMDBQSM-UHFFFAOYSA-N

SMILES: C(O)(=O)C1=C(Br)C=CC(F)=C1

Synonyms:

• 2-Bromo-5-Fluorobenzoate
• 2-Bromo-5-Fluorobenzoic
• 2-Bromo-5-Fluorobenzoicacid,98%
• 2-Bromo-5-fluorobenzoic acid,98%
• 5-Fluoro-2-bromobenzoic acid
• Benzoic acid, 2-bromo-5-fluoro-
• Buttpark 19\01-66
• Rarechem Al Bo 0747
• 2-Bromo-5-fluorobenzoic acid

2-Bromo-5-fluorobenzoic Acid

CAS: 394-28-5

Formula: C₇H₄BrFO₂

Purity: >98.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 219.01

Ref: 3B-B2722

2-Bromo-5-fluorobenzoic acid, 98+%

CAS: 394-28-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₄BrFO₂

Purity: 98+%

Color and Shape: White to cream, Powder

Molecular weight: 219.01

Ref: 02-B25394

2-Bromo-5-fluorobenzoic acid

CAS: 394-28-5

Formula: C₇H₄BrFO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 219.0079

Ref: IN-DA00335M

2-Bromo-5-fluorobenzoic acid

CAS: 394-28-5

2-Bromo-5-fluorobenzoic acid

Formula: C₇H₄BrFO₂

Purity: 98%

Color and Shape: white crystalline powder

Molecular weight: 219.01g/mol

Ref: 54-PC1825

2-Bromo-5-fluorobenzoic acid

CAS: 394-28-5

2-Bromo-5-fluorobenzoic acid is a polymerase inhibitor that inhibits the activity of the HIV-1 reverse transcriptase by competitive inhibition. It prevents the synthesis of viral DNA by binding to the RNA template and preventing chain elongation. This drug has been shown to be an effective treatment for some types of cancer, such as lung cancer, because it is not easily metabolized and can therefore reach high concentrations in tissues where it is needed. 2-Bromo-5-fluorobenzoic acid is synthesized from 5-(2′-bromophenoxy)benzothiazole and 2,3,4,5,6-pentafluorobenzoyl chloride in three steps. The synthesis involves bromination of benzothiazole with NBS followed by reaction with 4-fluoroaniline to give the intermediate which is then reacted with pentafluorobenzoyl chloride. This compound

Formula: C₇H₄BrFO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 219.01 g/mol

Ref: 3D-FB12070

2-Bromo-5-fluorobenzoic acid

CAS: 394-28-5

Formula: C₇H₄BrFO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 219.009

Ref: 10-F005471