Uridine, 5'-azido-5'-deoxy- is a nucleoside analog characterized by the presence of an azido group at the 5' position of the ribose sugar, replacing the hydroxyl group typically found in uridine. This modification imparts unique chemical properties, making it of interest in various biochemical applications, particularly in the fields of molecular biology and medicinal chemistry. The azido group can participate in click chemistry reactions, allowing for the conjugation of other molecules, which is valuable for labeling and tracking in cellular studies. The compound is typically soluble in polar solvents, and its stability can be influenced by environmental factors such as pH and temperature. As a nucleoside analog, it may also exhibit antiviral or anticancer properties, as many such compounds interfere with nucleic acid synthesis. However, its specific biological activity and potential therapeutic applications would require further investigation through empirical studies. Overall, Uridine, 5'-azido-5'-deoxy- represents a versatile tool in chemical biology and drug development.

Uridine, 5'-azido-5'-deoxy-

39483-48-2: Uridine, 5'-azido-5'-deoxy- is a nucleoside analog characterized by the presence of an azido group at the 5' position of the ribose sugar, replacing the hydroxyl group typically found in uridine. This modification imparts unique chemical properties, making it of interest in various biochemical applications, particularly in the fields of molecular biology and medicinal chemistry. The azido group can participate in click chemistry reactions, allowing for the conjugation of other molecules, which is valuable for labeling and tracking in cellular studies. The compound is typically soluble in polar solvents, and its stability can be influenced by environmental factors such as pH and temperature. As a nucleoside analog, it may also exhibit antiviral or anticancer properties, as many such compounds interfere with nucleic acid synthesis. However, its specific biological activity and potential therapeutic applications would require further investigation through empirical studies. Overall, Uridine, 5'-azido-5'-deoxy- represents a versatile tool in chemical biology and drug development.

<p>Nucleoside Derivatives - Azido nucleosides; 5’-Modified nucleosides</p>

5'-Azido-5'-deoxyuridine

<p>5'-Azido-5'-deoxyuridine is a synthetic nucleobase that is used in the synthesis of oligodeoxynucleotides. It has been shown to have an inhibitory effect on tumor cells, which may be due to its ability to interact with guanosine diphosphate (GDP) and prevent the formation of GTP. 5'-Azido-5'-deoxyuridine has also been shown to have an inhibitory effect on Mycobacterium tuberculosis and Mycobacterium avium complex, but does not affect other bacteria. 5'-Azido-5'-deoxyuridine interacts with RNA by binding to the phosphate group and inhibiting the synthesis of proteins and DNA.</p>

CAS 39483-48-2

Uridine, 5'-azido-5'-deoxy-

5'-Azido-5'-deoxyuridine

Ref: TM-TNU1166

5'-Azido-5'-deoxyuridine

Ref: 3D-NA163056