CAS 39492-01-8: Gabexate

Description: Gabexate, with the CAS number 39492-01-8, is a synthetic compound primarily recognized for its role as a protease inhibitor. It is classified as a serine protease inhibitor and is often utilized in clinical settings to manage conditions associated with excessive proteolytic activity, such as pancreatitis. Gabexate exhibits a high affinity for various serine proteases, including trypsin and thrombin, thereby modulating inflammatory responses and preventing tissue damage. The compound is typically administered intravenously and is known for its rapid onset of action. In terms of its chemical structure, Gabexate contains a carbon backbone with functional groups that facilitate its interaction with proteases. It is generally well-tolerated, although potential side effects may include allergic reactions or gastrointestinal disturbances. The pharmacokinetics of Gabexate indicate a relatively short half-life, necessitating careful dosing in therapeutic applications. Overall, Gabexate serves as an important pharmacological agent in the management of protease-related disorders.

Formula: C₁₇H₂₇N₃O₇S

InChI: InChI=1S/C16H23N3O4/c1-2-22-15(21)12-7-9-13(10-8-12)23-14(20)6-4-3-5-11-19-16(17)18/h7-10H,2-6,11H2,1H3,(H4,17,18,19)

InChI key: InChIKey=YKGYIDJEEQRWQH-UHFFFAOYSA-N

SMILES: O=C(OCC)C1=CC=C(OC(=O)CCCCCNC(=N)N)C=C1

Synonyms:

• (E)-amino({6-[4-(ethoxycarbonyl)phenoxy]-6-oxohexyl}imino)methanaminium methanesulfonate
• Benzoic acid, 4-((6-((aminoiminomethyl)amino)-1-oxohexyl)oxy)-, ethyl ester
• Ethyl 4-({6-[(Diaminomethylidene)Amino]Hexanoyl}Oxy)Benzoate
• Ethyl p-hydroxybenzoate 6-guanidinohexanoate
• Gabexate [INN]
• Gabexato
• Gabexato [INN-Spanish]
• Gabexatum
• Gabexatum [INN-Latin]
• Unii-4V7M9137X9
• p-Carbethoxyphenyl ε-guanidineocaproate
• p-Carbethoxyphenyl ε-guanidinocaproate

Gabexate Mesylate

CAS: 39492-01-856974-61-9

• Formula: C₁₆H₂₃N₃O₄·CH₄O₃S
• Purity: >97.0%(N)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 417.48

Gabexate

CAS: 39492-01-8

Gabexate is a protease inhibitor that is used to treat acute pancreatitis. It inhibits the …

• Formula: C₁₆H₂₃N₃O₄
• Purity: Min. 95%
• Molecular weight: 321.38 g/mol