CAS 3953-65-9

10H-Phenothiazine-10-propanamine, 2-chloro-N-methyl-, hydrochloride (1:1)

Description:

10H-Phenothiazine-10-propanamine, 2-chloro-N-methyl-, hydrochloride (1:1), commonly known by its CAS number 3953-65-9, is a chemical compound that belongs to the phenothiazine class, which is characterized by a tricyclic structure containing sulfur and nitrogen atoms. This compound typically exhibits properties associated with its phenothiazine backbone, including potential pharmacological activity, particularly as an antipsychotic or tranquilizing agent. The presence of the 2-chloro-N-methyl group suggests modifications that may enhance its biological activity or alter its pharmacokinetic properties. As a hydrochloride salt, it is likely to be more soluble in water, facilitating its use in pharmaceutical formulations. The compound may exhibit a range of biological effects, including interactions with neurotransmitter systems, which can be relevant in the treatment of various mental health disorders. Safety and handling precautions are essential, as with many chemical substances, due to potential toxicity or side effects associated with its use.

Formula: C₁₆H₁₇ClN₂S·ClH

InChI: InChI=1S/C16H17ClN2S.ClH/c1-18-9-4-10-19-13-5-2-3-6-15(13)20-16-8-7-12(17)11-14(16)19;/h2-3,5-8,11,18H,4,9-10H2,1H3;1H

InChI key: InChIKey=HDISSMQVJRSCEK-UHFFFAOYSA-N

SMILES: C(CCNC)N1C=2C(SC=3C1=CC=CC3)=CC=C(Cl)C2.Cl

Synonyms:

• 10H-Phenothiazine-10-propanamine, 2-chloro-N-methyl-, hydrochloride (1:1)
• 10H-Phenothiazine-10-propanamine, 2-chloro-N-methyl-, monohydrochloride
• Chlorpromazine EP impurity D Hydrochloride
• Demethylchlorpromazine hydrochloride
• Desmethylchloropromazine hydrochloride
• Desmethylchlorpromazine hydrochloride
• Mono-N-demethylchloropromazine hydrochloride
• Mono-N-demethylchlorpromazine hydrochloride
• Phenothiazine, 2-chloro-10-(3-methylaminopropyl)-, hydrochloride
• Phenothiazine, 2-chloro-10-[3-(methylamino)propyl]-, hydrochloride
• Phenothiazine, 2-chloro-10-[3-(methylamino)propyl]-, monohydrochloride

Desmethylchlorpromazine Hydrochloride 1.0 mg/ml in Methanol (as free base)

CAS: 3953-65-9

Color and Shape: Single Solution

Ref: 61-AMP0420.07-01

Desmethylchlorpromazine Hydrochloride

CAS: 3953-65-9

Color and Shape: Neat

Ref: 61-FOR0420.07

Chlorpromazine EP Impurity D HCl

CAS: 3953-65-9

Formula: C₁₆H₁₇ClN₂S·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 304.84 36.46

Ref: 4Z-C-125014

Chlorpromazine EP Impurity D (as Hydrochloride)

Controlled Product

CAS: 3953-65-9

Formula: C₁₆H₁₇ClN₂S·ClH

Color and Shape: Neat

Molecular weight: 341.30

Ref: 86-MM0420.07

Chlorpromazine EP Impurity D

CAS: 3953-65-9

Formula: C₁₆H₁₇ClN₂SHCl

Molecular weight: 304.8 : 36.5

Ref: ST-EA-CP-C19004

Demethyl Chlorpromazine Hydrochloride

Controlled Product

CAS: 3953-65-9

Impurity Chlorpromazine EP Impurity D
Applications A metabolite of Chlorpromazine (C424750).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Neuhoff, E., et al.: Archiv. der Pharmazie, 288, 400 (1955), Tomita, M., et al.: Chem. Pharm. Bull., 16, 688 (1968),

Formula: C₁₆H₁₇ClN₂S·ClH

Color and Shape: White

Molecular weight: 341.3

Ref: TR-D230835

Demethyl chlorpromazine hydrochloride

CAS: 3953-65-9

Chlorpromazine is a phenothiazine antipsychotic drug that is used to treat schizophrenia and other mental disorders. It is also used in the treatment of nausea, vomiting, and hiccups. Chlorpromazine binds to the D2 receptor in the brain, which blocks dopamine from binding to this receptor. In addition to its effects on dopamine receptors, chlorpromazine also inhibits phosphodiesterase activity and n-oxide formation. These effects are thought to be responsible for chlorpromazine's ability to inhibit tumor growth and prolong survival in some cancer patients. Chlorpromazine has been shown to inhibit filamentous fungi by inhibiting kinesin-like proteins that are essential for cell division. This drug also has low potency against cyclic nucleotide phosphodiesterases (PDEs) and may act as an inhibitor of PDE4B1 which is involved in the inflammatory response.

Formula: C₁₆H₁₈Cl₂N₂S

Purity: Min. 95%

Color and Shape: White/Off-White Solid

Molecular weight: 341.3 g/mol

Ref: 3D-FD20987