CAS 39546-32-2

Isonipecotamide

Description:

Isonipecotamide, with the CAS number 39546-32-2, is a chemical compound that belongs to the class of amides. It is derived from isonipecotic acid, which is a bicyclic compound featuring a piperidine ring. Isonipecotamide is characterized by its potential pharmacological properties, particularly in the context of its use as a central nervous system agent. The compound exhibits a moderate degree of solubility in polar solvents, which is typical for amides, and it may possess functional groups that contribute to its reactivity and interaction with biological systems. Its molecular structure includes nitrogen and carbon atoms, which are integral to its activity. While specific applications and detailed biological effects may vary, isonipecotamide is of interest in medicinal chemistry for its potential therapeutic effects. As with many chemical substances, safety and handling precautions are essential due to its biological activity, and further research is often necessary to fully elucidate its properties and applications.

Formula: C₆H₁₃N₂O

InChI: InChI=1/C6H12N2O/c7-6(9)5-1-3-8-4-2-5/h5,8H,1-4H2,(H2,7,9)/p+1

InChI key: InChIKey=DPBWFNDFMCCGGJ-UHFFFAOYSA-N

SMILES: C(N)(=O)C1CCNCC1

Synonyms:

• 4-(Aminocarbonyl)piperidine
• 4-Carbamoylpiperidine
• 4-Carbamoylpiperidinium
• 4-Carboxamidopiperidine
• 4-Piperidinecarboxamide
• 4-Piperidylcarboxamide
• Hexahydroisonicotinamide
• NSC 82318
• Piperidine-4-Carboxamide
• Piperidine-4-carboxylic acid amide

Isonipecotamide, 98%

CAS: 39546-32-2

Isonipecotamide is used as a reactant for the preparation of Survival motor neuron (SMN) protein modulators, orally available naphthyridine protein kinase D inhibitors and heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase. It is also used to prepare phosphodiesterase 5

Formula: C₆H₁₂N₂O

Purity: 98%

Color and Shape: White to pale yellow, Powder or crystalline powder

Molecular weight: 128.18

Ref: 02-A13442

4-Piperidinecarboxamide

CAS: 39546-32-2

Formula: C₆H₁₂N₂O

Purity: 97%

Color and Shape: Solid

Molecular weight: 128.1723

Ref: IN-DA00I7S5

Isonipecotamide

CAS: 39546-32-2

Formula: C₆H₁₂N₂O

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 128.18

Ref: 7W-GK0948

Piperidine-4-carboxamide

CAS: 39546-32-2

Piperidine-4-carboxamide

Formula: C₆H₁₂N₂O

Purity: 95%

Color and Shape: white solid

Molecular weight: 128.17g/mol

Ref: 54-OR28687

Isonipecotamide

CAS: 39546-32-2

Formula: C₆H₁₂N₂O

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 128.18

Ref: 3B-I0255

Isonipecotamide

CAS: 39546-32-2

Applications Anesthetic, analgesic, antimicrobial and cooling agent for prevention or treatment of skin irritation.
References Gaster, L.M., et al.: J. Med. Chem., 36, 4121 (1993),

Formula: C₆H₁₂N₂O

Color and Shape: Off-White

Molecular weight: 128.17

Ref: TR-I821800

4-Piperidinecarboxamide

CAS: 39546-32-2

Formula: C₆H₁₂N₂O

Purity: 95%

Color and Shape: Solid, Chunks or Crystalline Powder

Molecular weight: 128.175

Ref: 10-F037366

Hexahydroisonicotinamide

CAS: 39546-32-2

Hexahydroisonicotinamide (HNI) is a potent amyloid protein inhibitor that is structurally related to picolinic acid. HNI has been shown to be effective in the treatment of infectious diseases caused by bacteria, such as diazonium salt-resistant strains of Pseudomonas aeruginosa and Enterobacter cloacae. Hexahydroisonicotinamide is also active against methicillin-resistant Staphylococcus aureus (MRSA), which may be due to its structural similarity to picolinic acid. The molecular weight of HNI is 587.6, with a molecular formula of C9H11N3O2. It has been shown that hexahydroisonicotinamide inhibits the transfer reaction between an amide and piperidinium, as well as the phosphorylation of proteins by enzyme kinases. This drug binds to hydrated biphenyl molecules and inhibits their

Formula: C₆H₁₂N₂O

Purity: Min. 95%

Color and Shape: White To Yellow Solid

Molecular weight: 128.17 g/mol

Ref: 3D-FH34632