CAS 3963-95-9
:Methacycline hydrochloride
Description:
Methacycline hydrochloride is a semi-synthetic antibiotic belonging to the tetracycline class, characterized by its broad-spectrum antibacterial activity. It is primarily effective against a variety of Gram-positive and Gram-negative bacteria, as well as certain protozoa. The compound is known for its ability to inhibit protein synthesis in bacteria by binding to the 30S ribosomal subunit, thereby preventing the translation of mRNA. Methacycline hydrochloride is typically administered in its hydrochloride salt form, which enhances its solubility in water, facilitating oral or parenteral administration. The substance is often utilized in the treatment of various infections, including respiratory tract infections, urinary tract infections, and certain skin conditions. Its pharmacokinetic properties include moderate absorption and distribution in body tissues, with a relatively long half-life, allowing for less frequent dosing. However, like other tetracyclines, it may cause side effects such as gastrointestinal disturbances and photosensitivity. Due to the potential for bacterial resistance, its use is often guided by susceptibility testing.
Formula:C22H22N2O8·ClH
InChI:InChI=1S/C22H22N2O8.ClH/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;/h4-6,10,14-15,17,25,27-29,32H,1H2,2-3H3,(H2,23,31);1H/t10-,14-,15+,17+,22+;/m1./s1
InChI key:InChIKey=VZQARNDJLLWXGL-CCHMMTNSSA-N
SMILES:O[C@]12[C@]([C@H](N(C)C)C(O)=C(C(N)=O)C1=O)([C@@H](O)[C@]3(C(=C2O)C(=O)C=4C(C3=C)=CC=CC4O)[H])[H].Cl
Synonyms:- (2Z,4S,4Ar,5S,5Ar,12As)-2-[Amino(Hydroxy)Methylidene]-4-(Dimethylamino)-5,10,11,12A-Tetrahydroxy-6-Methylidene-4A,5A,6,12A-Tetrahydrotetracene-1,3,12(2H,4H,5H)-Trione Hydrochloride
- (4S,4Ar,5S,5Ar,12As)-4-(Dimethylamino)-3,5,10,12,12A-Pentahydroxy-6-Methylidene-1,11-Dioxo-1,4,4A,5,5A,6,11,12A-Octahydrotetracene-2-Carboxamide
- (4S,4Ar,5S,5Ar,12As)-4-(Dimethylamino)-3,5,10,12,12A-Pentahydroxy-6-Methylidene-1,11-Dioxo-1,4,4A,5,5A,6,11,12A-Octahydrotetracene-2-Carboxamide Hydrochloride (1:1)
- 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-, hydrochloride (1:1), (4S,4aR,5S,5aR,12aS)-
- 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-, monohydrochloride
- 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-, monohydrochloride, (4S,4aR,5S,5aR,12aS)-
- 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-, monohydrochloride, [4S-(4α,4aα,5α,5aα,12aα)]-
- 4-(Dimethylamino)-3,5,10,12,12A-Pentahydroxy-6-Methylidene-1,11-Dioxo-1,4,4A,5,5A,6,11,12A-Octahydrotetracene-2-Carboxamide Hydrochloride (1:1)
- 6-Demethyl-6-Deoxy-6-Methyleneoxytetracycline Monohydrochloride
- 6-Demethyl-6-Deoxy-6-Methyleneoxytetracyclne Hydrochloride
- 6-Demethyl-6-deoxy-5-hydroxy-6-methylenetetracycline hydrochloride
- 6-Demethyl-6-deoxy-6-methylene-5-hydroxytetracycline hydrochloride
- 6-Methylene-5-hydroxytetracycline chlorohydrate
- 6-Methylene-5-hydroxytetracycline hydrochloride
- 6-Methyleneoxytetracycline hydrochloride
- Adriamicina
- Ciclobiotic
- Germiciclin
- Londomycin
- Metacyclin hydrochloride
- Metacycline
- Metacycline Hcl
- Metacycline Hydrochloride
- Metadomus
- Metaryclinehcl
- Methacycline Hcl
- Methacycline Hydrochloride Bp73/Usp25
- Methacycline monohydrochloride
- Metilenbiotic
- Optimycin
- Physiomycine
- See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 16 products.
Methacycline Hydrochloride
CAS:Tetracyclines and their derivatives; salts thereofFormula:C22H22N2O8·ClHColor and Shape:Yellow PowderMolecular weight:478.11429Methacycline hydrochloride
CAS:Methacycline hydrochloride, a broad-spectrum antibiotic, is a slow-excreted tetracycline derivative with prolonged blood levels.Formula:C22H23ClN2O8Purity:99.02% - ≥98%Color and Shape:SolidMolecular weight:478.88Methacycline Hydrochloride
CAS:Formula:C22H23ClN2O8Purity:98%Color and Shape:SolidMolecular weight:478.8796Metacycline hydrochloride
CAS:Controlled ProductFormula:C22H22N2O8·ClHColor and Shape:NeatMolecular weight:478.88Metacycline Hydrochloride
CAS:Controlled ProductFormula:C22H22N2O8·ClHColor and Shape:NeatMolecular weight:478.88Metacycline hydrochloride 100 µg/mL in Acetonitrile
CAS:Formula:C22H22N2O8·ClHColor and Shape:Single SolutionMolecular weight:478.88Metacycline hydrochloride
CAS:Metacycline hydrochlorideFormula:C22H23ClN2O8Color and Shape:YellowMolecular weight:478.8796Methacycline Hydrochloride
CAS:Controlled ProductApplications Broad spectrum, semisynthetic antibiotic related to Tetracycline. Antibacterial.
References Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Chodosh, S., et al.: Chest, 69, 587 (1976),Formula:C22H22N2O8·ClHColor and Shape:YellowMolecular weight:478.88Methacycline HCl
CAS:Methacycline HCl is a tetracycline antibiotic with action on bacterial protein synthesis by binding to the 30S ribosomal subunit and is used for treating bacterial infections such as respiratory and urinary tract infections.
Formula:C22H22N2O8·HClPurity:Min. 95%Color and Shape:PowderMolecular weight:478.88 g/molRef: 3D-AM65078
Discontinued product
