CAS 39637-99-5: (R)-(-)-^a-Methoxy-^a-(trifluoromethyl)phenylacetyl chloride
Description:(R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride, with the CAS number 39637-99-5, is a chemical compound characterized by its unique functional groups and stereochemistry. It features a phenylacetyl chloride moiety, which is a reactive acyl chloride, making it useful in acylation reactions. The presence of the methoxy group and the trifluoromethyl group contributes to its chemical reactivity and polarity, influencing its solubility and interaction with other molecules. The (R)-(-) designation indicates that the compound has a specific chiral configuration, which can affect its biological activity and interaction with chiral environments. This compound is typically used in organic synthesis, particularly in the preparation of pharmaceuticals and agrochemicals, due to its ability to introduce the trifluoromethyl group, which is known to enhance the metabolic stability and lipophilicity of drug candidates. Safety precautions should be taken when handling this compound, as it may be corrosive and toxic.
Formula:C10H8ClF3O2
InChI:InChI=1/C10H8ClF3O2/c1-16-9(8(11)15,10(12,13)14)7-5-3-2-4-6-7/h2-6H,1H3/t9-/m0/s1
- Synonyms:
- (-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride
- Benzeneacetyl chloride, alpha-methoxy-alpha-(trifluoromethyl)-, (R)-

(R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl Chloride [for Determination of the optical purity of Alcohols and Amines]
Ref: 3B-M1104
1g | 301.00 € | ||
100mg | 72.00 € |

(R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl Chloride (ca. 18% in Dichloromethane, ca. 1.0mol/L) [for Determination of the optical purity of Alcohols and Amines]
Ref: 3B-M2215
5g | 279.00 € |

(R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride, 98+%
Ref: 02-L14325
1g | 468.00 € | ||
50mg | 54.00 € | ||
250mg | 150.00 € |

(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl Chloride
Ref: IN-DA003CHN
1g | 670.00 € | ||
5g | To inquire | ||
50mg | 91.00 € | ||
100mg | 122.00 € | ||
250mg | 194.00 € |

(2R)-(-)-2-Methoxy-2-phenyl-3,3,3-trifluoropropanoyl chloride
Ref: 54-PC5063L
1g | 220.00 € | ||
5g | 996.00 € | ||
250mg | 104.00 € |

(R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride, 98+%
Ref: AC-26412
1g | 367.00 € | ||
250mg | 131.00 € |

(R)-(-)-a-Methoxy-a-trifluoromethylphenylacetyl chloride, ca. 18% solution in Dichloromethane (ca. 1
Ref: 54-PC57487
1g | 929.00 € | ||
5g | 4,027.00 € | ||
100mg | 195.00 € | ||
250mg | 361.00 € |

(R)-(-)-a-Methoxy-a-trifluoromethylphenylacetyl chloride
Ref: 10-F009428
1g | 650.00 € | ||
5g | To inquire | ||
50mg | 141.00 € | ||
100mg | 148.00 € | ||
250mg | 264.00 € |

(R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride
Ref: 3D-FT105924
1g | 373.00 € | ||
2g | 597.00 € | ||
500mg | 331.00 € |