CAS 3964-54-3

3′-Chloro-4′-hydroxyacetanilide

Description:

3′-Chloro-4′-hydroxyacetanilide, also known by its CAS number 3964-54-3, is an organic compound that belongs to the class of acetanilides. It features a chloro group and a hydroxy group on the aromatic ring, which significantly influence its chemical properties and reactivity. This compound typically appears as a solid and is characterized by its moderate solubility in organic solvents and limited solubility in water, owing to its hydrophobic acetanilide structure. The presence of the chloro substituent can enhance its reactivity in nucleophilic substitution reactions, while the hydroxy group can participate in hydrogen bonding, affecting its interaction with other molecules. 3′-Chloro-4′-hydroxyacetanilide may be utilized in various applications, including as an intermediate in the synthesis of pharmaceuticals and agrochemicals. Safety data indicates that, like many chlorinated compounds, it should be handled with care due to potential toxicity and environmental impact. Proper safety protocols should be followed when working with this substance in laboratory or industrial settings.

Formula: C₈H₈ClNO₂

InChI: InChI=1S/C8H8ClNO2/c1-5(11)10-6-2-3-8(12)7(9)4-6/h2-4,12H,1H3,(H,10,11)

InChI key: InChIKey=JULKJDRBSRRBHT-UHFFFAOYSA-N

SMILES: N(C(C)=O)C1=CC(Cl)=C(O)C=C1

Synonyms:

• 2-Chloro-4-acetamidophenol
• 2-Chloro-4-acetylaminophenol
• 4-Acetamido-2-chlorophenol
• 4-Acetylamino-2-chlorophenol
• Acetamide, N-(3-chloro-4-hydroxyphenyl)-
• Acetanilide, 3′-chloro-4′-hydroxy-
• N-(3-chloro-4-hydroxyphenyl)acetamide

3-Chloro-4-Hydroxyacetanilide

CAS: 3964-54-3

Formula: C₈H₈ClNO₂

Purity: 96%

Color and Shape: Solid

Molecular weight: 185.6076

Ref: IN-DA00C97M

Paracetamol EP Impurity C

CAS: 3964-54-3

Formula: C₈H₈ClNO₂

Color and Shape: Purple Solid

Molecular weight: 185.61

Ref: 4Z-A-0217

Paracetamol EP Impurity C

Controlled Product

CAS: 3964-54-3

Formula: C₈H₈ClNO₂

Color and Shape: Neat

Molecular weight: 185.61

Ref: 86-MM0042.09

3-Chloro-4-hydroxyacetanilide

CAS: 3964-54-3

3-Chloro-4-hydroxyacetanilide

Purity: 95%

Molecular weight: 185.61g/mol

Ref: 54-OR906989

Paracetamol EP Impurity C

CAS: 3964-54-3

Formula: C₈H₈ClNO₂

Molecular weight: 185.61

Ref: ST-EA-CP-P10003

4-Acetylamino-2-chlorophenol

Controlled Product

CAS: 3964-54-3

Impurity Paracetamol EP Impurity C/ Acetaminophen impurity C
Applications 4-Acetylamino-2-chlorophenol is an impuirty of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).
References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)

Formula: C₈H₈ClNO₂

Color and Shape: White To Light Purple

Molecular weight: 185.61

Ref: TR-A168175

N-(3-Chloro-4-hydroxyphenyl)acetamide

CAS: 3964-54-3

Formula: C₈H₈ClNO₂

Purity: 96%

Molecular weight: 185.61

Ref: 10-F078204

3-Chloro-4-hydroxyacetanilide

CAS: 3964-54-3

3-Chloro-4-hydroxyacetanilide is a chemical compound that belongs to the class of acetanilides. It has long-term toxicity and is used as a drug substance in the production of aniline derivatives. 3-Chloro-4-hydroxyacetanilide has been shown to be carcinogenic in hamsters. The long term exposure to this chemical was shown to cause liver damage and increased incidence of tumours in rats. This drug also contains impurities and traces of chloride, chlorine, and thionyl chloride, which are toxic substances that can cause irritation or burns on contact with skin or eyes.

Formula: C₈H₈ClNO₂

Purity: Min. 95%

Molecular weight: 185.61 g/mol

Ref: 3D-IC10365

N-(3-Chloro-4-hydroxyphenyl)acetamide

CAS: 3964-54-3

N-(3-Chloro-4-hydroxyphenyl)acetamide is a useful organic compound for research related to life sciences. The catalog number is T67206 and the CAS number is 3964-54-3.

Formula: C₈H₈ClNO₂

Color and Shape: Solid

Molecular weight: 185.61

Ref: TM-T67206