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CAS 3964-81-6

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Azatadine

Description:
Azatadine is an antihistamine that belongs to the class of compounds known as tricyclic antihistamines. It is primarily used for the treatment of allergic conditions, such as hay fever and other allergic rhinitis symptoms. The chemical structure of azatadine features a tricyclic framework, which contributes to its pharmacological properties. It acts as an antagonist at the H1 histamine receptor, thereby inhibiting the effects of histamine, a key mediator in allergic responses. Azatadine is known for its sedative effects, which can be attributed to its ability to cross the blood-brain barrier. In addition to its antihistaminic activity, it may exhibit anticholinergic properties, which can lead to side effects such as dry mouth and drowsiness. The substance is typically administered orally and is available in various formulations. As with any medication, it is important to consider potential interactions and contraindications when prescribing azatadine. Overall, its effectiveness in alleviating allergy symptoms makes it a valuable option in the management of allergic conditions.
Formula:C20H22N2
InChI:InChI=1S/C20H22N2/c1-22-13-10-16(11-14-22)19-18-7-3-2-5-15(18)8-9-17-6-4-12-21-20(17)19/h2-7,12H,8-11,13-14H2,1H3
InChI key:InChIKey=SEBMTIQKRHYNIT-UHFFFAOYSA-N
SMILES:CN1CCC(=C2C=3C(CCC=4C2=NC=CC4)=CC=CC3)CC1
Synonyms:
  • 11-(1-methylpiperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine (2Z)-but-2-enedioate (1:2)
  • 11-(1-methylpiperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
  • 5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 6,11-dihydro-11-(1-methyl-4-piperidinylidene)-
  • 5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 6,11-dihydro-11-(1-methyl-4-piperidylidene)-
  • 6,11-Dihydro-11-(1-methyl-4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
  • 6,11-Dihydro-11-(1-methyl-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine
  • Azatadina
  • Azatadina [INN-Spanish]
  • Azatadinum
  • Azatadinum [INN-Latin]
  • See more synonyms
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