CAS 3966-32-3

(-)-Methoxyphenylacetic acid

Description:

(-)-Methoxyphenylacetic acid, with the CAS number 3966-32-3, is an organic compound characterized by its aromatic structure and the presence of both a methoxy group and a carboxylic acid functional group. This compound typically appears as a white to off-white crystalline solid. It is known for its chiral nature, with the "(-)" designation indicating its specific enantiomeric form. The methoxy group contributes to its solubility in organic solvents, while the carboxylic acid group imparts acidic properties, allowing it to participate in various chemical reactions, such as esterification and amidation. (-)-Methoxyphenylacetic acid has applications in pharmaceuticals and organic synthesis, often serving as an intermediate in the production of more complex molecules. Its biological activity may also be of interest in medicinal chemistry, although specific pharmacological properties would require further investigation. Overall, this compound exemplifies the diverse functionalities that can arise from simple organic structures.

Formula: C₉H₁₀O₃

InChI: InChI=1S/C9H10O3/c1-12-8(9(10)11)7-5-3-2-4-6-7/h2-6,8H,1H3,(H,10,11)/t8-/m1/s1

InChI key: InChIKey=DIWVBIXQCNRCFE-MRVPVSSYSA-N

SMILES: [C@@H](C(O)=O)(OC)C1=CC=CC=C1

Synonyms:

• (-)-(R)-α-Methoxyphenylacetic acid
• (-)-(αR)-α-Methoxybenzeneacetic acid
• (-)-2-Methoxy-2-phenylacetic acid
• (-)-2-Methoxyphenylacetic acid
• (-)-Methoxyphenylacetic acid
• (-)-α-Methoxyphenylacetic acid
• (2R)-2-Methoxy-2-phenylacetic acid
• (2R)-2-Methoxy-2-phenylethanoic acid
• (2R)-O-Methylmandelic acid
• (2R)-methoxy(phenyl)ethanoate
• (2R)-methoxy(phenyl)ethanoic acid
• (R)-(-)-2-Methoxy-2-phenylacetic acid
• (R)-(-)-O-Methylmandelic acid
• (R)-(-)-α-MPA
• (R)-(-)-α-Methoxyphenylethanoic acid
• (R)-2-Methoxy-2-phenylethanoic acid
• (R)-2-Methoxyphenylacetic acid
• (R)-2-Phenyl-2-methoxyacetic acid
• (R)-Methoxy(phenyl)acetic acid
• (R)-Methoxyphenylacetic acid
• (R)-α-Methoxy-α-phenylacetic acid
• (R)-α-Methoxybenzeneacetic acid
• (R)-α-Methoxybenzeneethanoic acid
• <span class="text-smallcaps">D</span>-(-)-Methoxyphenylacetic acid
• <span class="text-smallcaps">D</span>-α-Methoxyphenylacetic acid
• Acetic acid, methoxyphenyl-, (R)-(-)-
• Benzeneacetic acid, α-methoxy-, (R)-

(R)-2-Methoxy-2-phenylacetic acid

CAS: 3966-32-3

Formula: C₉H₁₀O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 166.1739

Ref: IN-DA003C3B

(R)-(-)-α-methoxyphenylacetic acid

CAS: 3966-32-3

(R)-(-)-α-methoxyphenylacetic acid

Formula: C₉H₁₀O₃

Purity: 98%

Color and Shape: white solid

Molecular weight: 166.17g/mol

Ref: 54-OR960661

(R)-(-)-α-Methoxyphenylacetic Acid

CAS: 3966-32-3

Formula: C₉H₁₀O₃

Purity: >98.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 166.18

Ref: 3B-M0830

(R)-2-Methoxy-2-phenylacetic acid

CAS: 3966-32-3

Formula: C₉H₁₀O₃

Purity: 98%

Color and Shape: Solid, White to almost white powder

Molecular weight: 166.176

Ref: 10-F223096

(R)-(-)-α-Methoxyphenylacetic Acid

Controlled Product

CAS: 3966-32-3

Applications (R)-(-)-α-Methoxyphenylacetic Acid is a useful synthetic intermediate. It is used as a reactant in the synthesis of dopamine receptor agonists. It can also be used to prepare hydroxytriamides as potent γ-secretase inhibitors.
References Biswas, S., et al.: J. Med. Chem., 51, 101 (2008); Prasad, C., et al.: Bioorg. Med. Chem. Lett., 14, 1917 (2004)

Formula: C₉H₁₀O₃

Color and Shape: Neat

Molecular weight: 166.17

Ref: TR-M265740