CAS 39672-75-8

(9β,11β,16α)-9,11-Epoxy-21-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione

Description:

The chemical substance known as "(9β,11β,16α)-9,11-Epoxy-21-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione," with the CAS number 39672-75-8, is a synthetic steroid compound. It features a complex structure characterized by a steroid backbone, which includes multiple functional groups such as epoxy, hydroxy, and ether moieties. The presence of the epoxy group indicates potential reactivity, while the hydroxy group can participate in hydrogen bonding and influence solubility and biological activity. This compound is likely to exhibit hormonal activity, given its structural similarity to natural steroid hormones. Its unique substituents, including the isopropylidene ether, may affect its pharmacokinetics and receptor interactions. Such compounds are often studied for their potential therapeutic applications, particularly in fields like endocrinology and pharmacology. However, specific biological activities, toxicity, and therapeutic uses would require further investigation through empirical studies and clinical trials.

Formula: C₂₄H₃₀O₆

InChI: InChI=1S/C24H30O6/c1-20(2)28-18-10-16-15-6-5-13-9-14(26)7-8-21(13,3)23(15)19(29-23)11-22(16,4)24(18,30-20)17(27)12-25/h7-9,15-16,18-19,25H,5-6,10-12H2,1-4H3/t15-,16-,18+,19-,21-,22-,23+,24+/m0/s1

InChI key: InChIKey=LAOLPAAORRPVAA-ZNGCHRITSA-N

SMILES: C[C@@]12[C@@]34[C@@](O3)(C[C@@]5(C)[C@]([C@@]4(CCC1=CC(=O)C=C2)[H])(C[C@@]6([C@@]5(C(CO)=O)OC(C)(C)O6)[H])[H])[H]

Synonyms:

• 9,11β-Epoxy-16α,17,21-trihydroxy-9β-pregna-1,4-diene-3,20-dione, 16,17-acetonide
• Pregna-1,4-diene-3,20-dione, 9,11-epoxy-21-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (9β,11β,16α)-
• (9β,11β,16α)-9,11-Epoxy-21-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
• (6aS,6bS,7aS,8aS,8bS,11aR,12aS,12bS)-8b-(2-hydroxyacetyl)-6a,8a,10,10-tetramethyl-1,6a,7a,8,8a,8b,11a,12,12a,12b-decahydronaphtho[2',1':4,5]oxireno[2',3':5,6]indeno[1,2-d][1,3]dioxol-4(2H)-one
• Epoxydesonide
• Desonide Epoxy Impurity
• Desonide 9, 11-Epoxide
• (6aS,6bS,7aS,8aS,8bS,11aR,12aS,12bS)-8b-(2-hydroxyacetyl)-6a,8a,10,10-tetramethyl-1,2,7a,8,8a,8b,11a,12,12a,12b-decahydronaphtho[2',1':4,5]oxireno[2',3':5,6]indeno[1,2-d][1,3]dioxol-4(6aH)-one
• Epoxy Acetonide
• Desonide Impurity 2
• 9-Desfluoro-9(11)-epoxy Triamcinolone Acetonide

(9β,11β,16α)-9,11-Epoxy-21-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione

CAS: 39672-75-8

Formula: C₂₄H₃₀O₆

Purity: 95%

Color and Shape: Solid

Molecular weight: 414.4914

Ref: IN-DA00JO0X

Triamcinolone Acetonide Impurity 2

CAS: 39672-75-8

Formula: C₂₄H₃₀O₆

Molecular weight: 414.50

Ref: 4Z-T-5315

9-Desfluoro-9(11)-epoxy Triamcinolone Acetonide

Controlled Product

CAS: 39672-75-8

Stability Hygroscopic
Applications 9-Desfluoro-9(11)-epoxy Triamcinolone Acetonide is an impurity of Triamcinolone Acetonide (T767165) which is an antiasthmatic (inhalant) and antiallergic (nasal).
References Florey, K., et al.: Anal. Profiles Drug Subs., 1, 397 (1972), Bernstein, I.L., et al.: Chest, 81, 20 (1982),

Formula: C₂₄H₃₀O₆

Color and Shape: White To Off-White

Molecular weight: 414.4914

Ref: TR-D289855

9-Desfluoro-9(11)-epoxy triamcinolone acetonide

CAS: 39672-75-8

9-Desfluoro-9(11)-epoxy triamcinolone acetonide is a synthetic metabolite of the natural drug product 9-desfluoro-9(11)-epoxy triamcinolone acetonide. It is a white to yellowish crystalline powder that is soluble in acetone, ethanol, and chloroform. It has been used as an analytical standard for HPLC and GC analysis. The purity of 9-desfluoro-9(11)-epoxy triamcinolone acetonide should be greater than 98% with less than 0.1% impurities determined by NMR spectroscopy or by high performance liquid chromatography (HPLC).

Formula: C₂₄H₃₀O₆

Purity: Min. 95%

Molecular weight: 414.50 g/mol

Ref: 3D-PBA67275

Triamcinolone Acetonide Impurity 2

CAS: 39672-75-8

Formula: C₂₄H₃₀O₆

Molecular weight: 414.5

Ref: ST-EA-CP-T98022

Epoxydesonide

CAS: 39672-75-8

Formula: C₂₄H₃₀O₆

Molecular weight: 414.5

Ref: ST-EA-CP-D99007