CAS 3970-37-4

1-Bromo-2-chloro-3-nitrobenzene

Description:

1-Bromo-2-chloro-3-nitrobenzene is an aromatic compound characterized by the presence of three distinct substituents on a benzene ring: a bromine atom, a chlorine atom, and a nitro group. This compound is classified as a halogenated nitrobenzene derivative. It typically appears as a pale yellow solid and is known for its moderate solubility in organic solvents such as ethanol and ether, while being less soluble in water. The presence of the bromine and chlorine atoms contributes to its reactivity, making it useful in various chemical synthesis processes, including the production of pharmaceuticals and agrochemicals. The nitro group is a strong electron-withdrawing group, which influences the compound's reactivity and stability. Additionally, 1-bromo-2-chloro-3-nitrobenzene can undergo electrophilic substitution reactions, making it a valuable intermediate in organic synthesis. Safety precautions should be taken when handling this compound, as it may pose health risks due to its halogenated nature and potential toxicity.

Formula: C₆H₃BrClNO₂

InChI: InChI=1/C6H3BrClNO2/c7-4-2-1-3-5(6(4)8)9(10)11/h1-3H

InChI key: InChIKey=JNIDAGAFFKAPRV-UHFFFAOYSA-N

SMILES: N(=O)(=O)C1=C(Cl)C(Br)=CC=C1

Synonyms:

• Benzene, 1-Bromo-2-Chloro-3-Nitro-
• 1-Bromo-2-chloro-3-nitrobenzene
• 1-BROMO-2-CHLORO-3-NITROBENZENE ISO 9001：2015 REACH
• oro-3-nitrobenzene

1-Bromo-2-Chloro-3-Nitrobenzene

CAS: 3970-37-4

Formula: C₆H₃BrClNO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 236.4505

Ref: IN-DA003630

1-Bromo-2-chloro-3-nitrobenzene

CAS: 3970-37-4

1-Bromo-2-chloro-3-nitrobenzene

Formula: C₆H₃BrClNO₂

Purity: 98%

Color and Shape: yellow powder

Molecular weight: 236.45g/mol

Ref: 54-OR301062

3-Bromo-2-chloronitrobenzene

CAS: 3970-37-4

Formula: C₆H₃BrClNO₂

Purity: 98%

Color and Shape: Solid, Low Melting Solid

Molecular weight: 236.45

Ref: 10-F062570

1-Bromo-2-chloro-3-nitrobenzene

Controlled Product

CAS: 3970-37-4

Applications 1-Bromo-2-chloro-3-nitrobenzene is a reagent used in pharmaceutical synthesis. Used in the synthesis of benzodiazepinone bromodomain inhibitor CPI-​637 which may be applicable to cancer therapies.
References Taylor, A. et al.: ACS. Med. Chem. Lett., 7, 531 (2016);

Formula: C₆H₃BrClNO₂

Color and Shape: Neat

Molecular weight: 236.45

Ref: TR-B682568