CAS 397864-44-7
:Fluticasone furoate
Description:
Fluticasone furoate is a synthetic corticosteroid with anti-inflammatory properties, primarily used in the treatment of respiratory conditions such as asthma and allergic rhinitis. It is characterized by its high affinity for the glucocorticoid receptor, which enhances its efficacy in reducing inflammation and immune responses. The substance is typically administered via inhalation or nasal spray, allowing for targeted delivery to the respiratory system. Fluticasone furoate exhibits a long duration of action, which supports once-daily dosing. Its chemical structure includes a fluorinated steroid backbone, contributing to its potency and stability. The compound is generally well-tolerated, with a side effect profile that may include local irritation or, in rare cases, systemic effects associated with corticosteroid use. As a member of the fluticasone family, it is often compared to other corticosteroids in terms of efficacy and safety, making it a valuable option in managing chronic inflammatory conditions.
Formula:C27H29F3O6S
InChI:InChI=1S/C27H29F3O6S/c1-14-9-16-17-11-19(29)18-10-15(31)6-7-24(18,2)26(17,30)21(32)12-25(16,3)27(14,23(34)37-13-28)36-22(33)20-5-4-8-35-20/h4-8,10,14,16-17,19,21,32H,9,11-13H2,1-3H3/t14-,16+,17+,19+,21+,24+,25+,26+,27+/m1/s1
InChI key:InChIKey=XTULMSXFIHGYFS-VLSRWLAYSA-N
SMILES:O(C(=O)C1=CC=CO1)[C@@]2(C(SCF)=O)[C@]3(C)[C@@](C[C@H]2C)([C@]4([C@](F)([C@@H](O)C3)[C@]5(C)C([C@@H](F)C4)=CC(=O)C=C5)[H])[H]
Synonyms:- (6alpha,11beta,16alpha,17alpha)-6,9-Difluoro-17-(((fluoromethyl)thio)carbonyl)-11-hydroxy-16-methyl-3-oxoandrosta-1,4-dien-17-yl-2-furancarboxylate
- 6alpha,9-Difluoro-17-(((fluoromethyl)sulfanyl)carbonyl)-11beta-hydroxy-16alpha-methyl-3-oxoandrosta-1,4-dien-17alpha-yl furan-2-carboxylate
- 6α,9α-Difluoro-17α-[(2-furanylcarbonyl)oxy]-11β-hydroxy-16α-methyl-3-oxoandrosta-1,4-diene-17β-carbothioic acid S-fluoromethyl ester
- Alisade
- Allermist
- Androsta-1,4-diene-17-carbothioic acid, 6,9-difluoro-17-((2- furanylcarbonyl)oxy)-11-hydroxy-16-methyl-3-oxo-, S-(fluoromethyl) ester, (6alpha,11beta,16alpha,17alpha)-
- Androsta-1,4-diene-17-carbothioic acid, 6,9-difluoro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methyl-3-oxo-, S-(fluoromethyl) ester, (6α,11β,16α,17α)-
- Avamys
- Furamist
- Gsk 685 698
- Gsk 685698
- Gw 685698X
- Unii-Js86977Wnv
- Veramyst
- See more synonyms
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Found 12 products.
FLUTICASONE FUROATE FOR SYSTEM SUITABILITY CRS
CAS:<p>FLUTICASONE FUROATE FOR SYSTEM SUITABILITY CRS</p>FLUTICASONE FUROATE FOR PEAK IDENTIFICATION CRS
CAS:<p>FLUTICASONE FUROATE FOR PEAK IDENTIFICATION CRS</p>Fluticasone Furoate
CAS:Formula:C27H29F3O6SColor and Shape:White To Off-White SolidMolecular weight:538.58Fluticasone Furoate-d3
CAS:Formula:C27H26D3F3O6SColor and Shape:White To Off-White SolidMolecular weight:541.60Fluticasone Impurity 19
CAS:Formula:C26H29FO6SColor and Shape:White To Off-White SolidMolecular weight:488.57Fluticasone Furoate
CAS:Controlled Product<p>Applications A synthetic corticosteroid derived from fluticasone for treatment of seasonal allergic rhinitis.<br>References DeWester, J., et al.: Allergy Asthma Proc., 24, 331 (2003), Hughes, S., et al.: Drug Metab. Dispos., 36, 2337 (2008), Meltzer, E., et al.: Clin. Drug Investig., 29, 79 (2009),<br></p>Formula:C27H29F3O6SColor and Shape:NeatMolecular weight:538.58Fluticasone furoate
CAS:<p>Fluticasone furoate is a nasal spray that contains fluticasone and furoate. It is used for the treatment of bacterial rhinosinusitis, nasal polyps, allergic rhinitis, and other allergic symptoms. Fluticasone furoate has been shown to be effective in vivo in a polymer model of nasal inflammation. This drug also has anti-inflammatory activity by inhibiting the release of inflammatory mediators from mast cells and leukocytes. Fluticasone furoate has been shown to be statistically significantly more effective than fluticasone alone at relieving symptoms of both seasonal and perennial allergic rhinitis.</p>Formula:C27H29F3O6SPurity:(Hplc) 98 To 102%Color and Shape:White PowderMolecular weight:538.58 g/molFluticasone furoate
CAS:<p>Fluticasone furoate (Avamys), a potent, trifluorinated steroid with anti-inflammatory effects, treats allergic rhinitis.</p>Formula:C27H29F3O6SPurity:99.82%Color and Shape:SolidMolecular weight:538.58
