CAS 398-36-7

4-(Trifluoromethyl)biphenyl

Description:

4-(Trifluoromethyl)biphenyl, with the CAS number 398-36-7, is an organic compound characterized by the presence of a trifluoromethyl group (-CF3) attached to one of the phenyl rings in a biphenyl structure. This compound typically appears as a colorless to pale yellow liquid or solid, depending on the temperature and purity. It is known for its relatively high thermal stability and low volatility, making it suitable for various applications in organic synthesis and materials science. The trifluoromethyl group imparts unique electronic and steric properties, enhancing the compound's lipophilicity and influencing its reactivity. 4-(Trifluoromethyl)biphenyl is often utilized in the development of pharmaceuticals, agrochemicals, and as a building block in the synthesis of more complex fluorinated compounds. Additionally, it exhibits interesting interactions with biological systems, which can be leveraged in medicinal chemistry. However, like many fluorinated compounds, it should be handled with care due to potential environmental and health impacts.

Formula: C₁₃H₉F₃

InChI: InChI=1/C13H9F3/c14-13(15,16)12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9H

SMILES: c1ccc(cc1)c1ccc(cc1)C(F)(F)F

Synonyms:

• 4-(Trifluoromethyl)-Biphenyl
• 4-(trifluoroMethyl)-1,1'-biphenyl
• 1-phenyl-4-(trifluoromethyl)benzene
• 1,1'-Biphenyl, 4-(trifluoromethyl)-

4-(TRIFLUOROMETHYL)-BIPHENYL

CAS: 398-36-7

Formula: C₁₃H₉F₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 222.2058

Ref: IN-DA00C8MO

4-(Trifluoromethyl)biphenyl

CAS: 398-36-7

4-(Trifluoromethyl)biphenyl

Purity: 99%

Color and Shape: Off-White Solid

Molecular weight: 222.21g/mol

Ref: 54-PC520526

4-Trifluoromethylbiphenyl

CAS: 398-36-7

4-Trifluoromethylbiphenyl is a catalyst for cross-coupling reactions. It is used in the Suzuki reaction to bind a phosphine ligand. This molecule also binds to the ligand binding domain of human P450 enzymes. 4-Trifluoromethylbiphenyl has been shown to be orally bioavailable, and has various isomers. The solid form of this molecule undergoes cross-coupling reactions with phenylboronic acids in the presence of a phosphine ligand. 4-Trifluoromethylbiphenyl is an inorganic compound that was first synthesized by experiment in 1891. It was first isolated from coal tar, but today is usually synthesized from benzene and chloroform in a solid form.

Formula: C₁₃H₉F₃

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 222.21 g/mol

Ref: 3D-FT77917

4-TRIFLUOROMETHYLBIPHENYL

CAS: 398-36-7

Formula: C₁₃H₉F₃

Purity: 97%

Color and Shape: Solid, White to cream or pale brown solid

Molecular weight: 222.21

Ref: 10-F304055