CAS 39809-25-1: Penciclovir

Description: Penciclovir is an antiviral medication primarily used for the treatment of herpes simplex virus infections, particularly in cases of recurrent genital herpes and cold sores. It is a synthetic nucleoside analog of guanine, which means it mimics the structure of nucleotides, allowing it to interfere with viral DNA synthesis. Penciclovir exhibits a high affinity for the viral enzyme thymidine kinase, which is crucial for its activation within infected cells. The compound is characterized by its relatively low solubility in water, which influences its pharmacokinetics and bioavailability. Penciclovir is typically administered topically in cream form, allowing for localized treatment with minimal systemic absorption. Its mechanism of action involves selective inhibition of viral DNA polymerase, thereby preventing the replication of the virus. While generally well-tolerated, potential side effects may include local irritation or allergic reactions at the application site. Overall, penciclovir represents an important therapeutic option in managing herpes virus infections, particularly for patients seeking topical treatment alternatives.

Formula: C₁₀H₁₅N₅O₃

InChI: InChI=1S/C10H15N5O3/c11-10-13-8-7(9(18)14-10)12-5-15(8)2-1-6(3-16)4-17/h5-6,16-17H,1-4H2,(H3,11,13,14,18)

InChI key: InChIKey=JNTOCHDNEULJHD-UHFFFAOYSA-N

SMILES: O=C1N=C(N)NC2=C1N=CN2CCC(CO)CO

Synonyms:

• 2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-3,9-dihydropurin-6-one
• BRL 39123
• 9-[4-Hydroxy-3-(hydroxymethyl)butyl]guanine
• 2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-3,9-dihydro-6H-purin-6-one
• 2-Amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)butyl]-6H-purin-6-one
• 6H-Purin-6-one, 2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)butyl]-
• Penciclovir

Penciclovir

CAS: 39809-25-1

• Formula: C₁₀H₁₅N₅O₃
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 253.26

Penciclovir

CAS: 39809-25-1

Penciclovir, a herpesvirus inhibitor, blocks DNA replication in HSV cells by disrupting enzyme activity.

• Formula: C₁₀H₁₅N₅O₃
• Purity: 98.84%
• Color and Shape: White Crystalline Solid
• Molecular weight: 253.26

2-amino-9-[1,1,2,2-tetradeuterio-4-hydroxy-3-(hydroxymethyl)butyl]-3H-purin-6-one

CAS: 39809-25-1

• Formula: C₁₀H₁₅N₅O₃
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 253.2578

Penciclovir

CAS: 39809-25-1

• Formula: C₁₀H₁₅N₅O₃
• Color and Shape: White To Off-White Solid
• Molecular weight: 253.26

Penciclovir

CAS: 39809-25-1

• Purity: 99%
• Molecular weight: 253.26g/mol

Penciclovir

CAS: 39809-25-1

• Purity: ≥98%
• Molecular weight: 253.26g/mol

Penciclovir

CAS: 39809-25-1

• Formula: C₁₀H₁₅N₅O₃
• Purity: ≥ 98.0%
• Color and Shape: White to off-white powder
• Molecular weight: 253.26

2-Amino-9-(4-hydroxy-3-(hydroxymethyl)butyl)-1H-purin-6(9H)-one

CAS: 39809-25-1

• Purity: 98%
• Molecular weight: 253.261993408203

Penciclovir-d4

CAS: 39809-25-1

• Formula: C₁₀H₁₁D₄N₅O₃
• Molecular weight: 257.28

Penciclovir

CAS: 39809-25-1

Applications An antiviral. References Weinberg, A., et al.: Antimicrob. Ag. Chemother., 36, 2037 (1992), McMeekin, …

• Formula: C₁₀H₁₅N₅O₃
• Color and Shape: Neat
• Molecular weight: 253.26

Penciclovir

CAS: 39809-25-1

Anti-viral; DNA polymerase and replication inhibitor

• Formula: C₁₀H₁₅N₅O₃
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 253.26 g/mol

Penciclovir - Bio-X ™

CAS: 39809-25-1

Penciclovir is an antiviral agent and acyclic guanine derivative that has proven efficient in the …

• Formula: C₁₀H₁₅N₅O₃
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 253.26 g/mol