CAS 398507-55-6

Lodenafil carbonate

Description:

Lodenafil carbonate is a chemical compound that belongs to the class of phosphodiesterase type 5 (PDE5) inhibitors, which are primarily used in the treatment of erectile dysfunction. It is characterized by its ability to enhance blood flow to the penis by inhibiting the breakdown of cyclic guanosine monophosphate (cGMP), a molecule that plays a crucial role in vasodilation. The compound is typically administered in oral form and has a specific mechanism of action that involves the relaxation of smooth muscle tissues. Lodenafil carbonate is known for its relatively favorable pharmacokinetic profile, which includes a moderate onset of action and duration of effect. Additionally, it may exhibit a lower incidence of side effects compared to some other PDE5 inhibitors, making it a subject of interest in clinical research. As with any pharmaceutical agent, its use should be guided by a healthcare professional, considering potential interactions and contraindications. Overall, Lodenafil carbonate represents a significant advancement in the therapeutic options available for managing erectile dysfunction.

Formula: C₄₇H₆₂N₁₂O₁₁S₂

InChI: InChI=1S/C47H62N12O11S2/c1-7-11-35-39-41(54(5)52-35)45(60)50-43(48-39)33-29-31(13-15-37(33)67-9-3)71(63,64)58-21-17-56(18-22-58)25-27-69-47(62)70-28-26-57-19-23-59(24-20-57)72(65,66)32-14-16-38(68-10-4)34(30-32)44-49-40-36(12-8-2)53-55(6)42(40)46(61)51-44/h13-16,29-30H,7-12,17-28H2,1-6H3,(H,48,50,60)(H,49,51,61)

InChI key: InChIKey=MVYUCRDXZXLFSB-UHFFFAOYSA-N

SMILES: C(CC)C=1C2=C(C(=O)N=C(N2)C3=C(OCC)C=CC(S(=O)(=O)N4CCN(CCOC(OCCN5CCN(S(=O)(=O)C6=CC(=C(OCC)C=C6)C=7NC8=C(C(=O)N7)N(C)N=C8CCC)CC5)=O)CC4)=C3)N(C)N1

Synonyms:

• 7H-Pyrazolo[4,3-d]pyrimidin-7-one, 5,5′-[carbonylbis[oxy-2,1-ethanediyl-4,1-piperazinediylsulfonyl(6-ethoxy-3,1-phenylene)]]bis[1,6-dihydro-1-methyl-3-propyl-
• 1-Piperazineethanol, 4-[[3-(4,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-, carbonate (2:1) (ester)
• Lodenafil carbonate
• 5,5′-[Carbonylbis[oxy-2,1-ethanediyl-4,1-piperazinediylsulfonyl(6-ethoxy-3,1-phenylene)]]bis[1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one]

Lodenafil carbonate

CAS: 398507-55-6

Lodenafil carbonate is a prodrug, orally used as a PDE5 inhibitor for ED treatment.

Formula: C₄₇H₆₂N₁₂O₁₁S₂

Color and Shape: Solid

Molecular weight: 1035.21

Ref: TM-T37325

Lodenafil Carbonate

CAS: 398507-55-6

Formula: C₄₇H₆₂N₁₂O₁₁S₂

Color and Shape: White To Off-White Solid

Molecular weight: 1035.21

Ref: 4Z-S-0641

Lodenafil carbonate

CAS: 398507-55-6

Formula: C₄₇H₆₂N₁₂O₁₁S₂

Color and Shape: Neat

Molecular weight: 1035.20

Ref: 04-C14644500

Lodenafil Carbonate

Controlled Product

CAS: 398507-55-6

Stability Hygroscopic
Applications Lodenafil carbonate is a new PDE-5 inhibitor used for oral therapy in erectile dysfunction.
References Rosen, R., et al.: Urology, 49, 822 (1997), Chew, K., et al.: J. Sex Med., 5, 928 (2008), Teixeira, C., et al.: Eur. J. Pharmacol., 591, 189 (2008),

Formula: C₄₇H₆₂N₁₂O₁₁S₂

Color and Shape: Neat

Molecular weight: 1035.20

Ref: TR-L469300

Lodenafil Carbonate

CAS: 398507-55-6

Formula: C₄₇H₆₂N₁₂O₁₁S₂

Molecular weight: 1035.21

Ref: ST-EA-CP-S2068