CAS 39856-50-3

5-Bromo-2-nitropyridine

Description:

5-Bromo-2-nitropyridine is an organic compound characterized by its heterocyclic structure, which includes a pyridine ring substituted with both a bromine atom and a nitro group. The presence of these substituents significantly influences its chemical properties and reactivity. Typically, the bromine atom, being a good leaving group, can facilitate nucleophilic substitution reactions, while the nitro group, known for its electron-withdrawing properties, can enhance the acidity of nearby hydrogen atoms and influence electrophilic aromatic substitution. This compound is often utilized in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals, due to its ability to serve as an intermediate in various chemical reactions. Additionally, 5-Bromo-2-nitropyridine exhibits moderate solubility in organic solvents, making it suitable for various laboratory applications. Safety considerations should be taken into account, as both brominated compounds and nitro compounds can pose health hazards. Proper handling and storage in accordance with safety guidelines are essential when working with this substance.

Formula: C₅H₃BrN₂O₂

InChI: InChI=1S/C5H3BrN2O2/c6-4-1-2-5(7-3-4)8(9)10/h1-3H

InChI key: InChIKey=ATXXLNCPVSUCNK-UHFFFAOYSA-N

SMILES: N(=O)(=O)C1=CC=C(Br)C=N1

Synonyms:

• 3-Bromo-6-nitropyridine
• 5-Bromo-2-nitropyridine
• Pyridine, 5-bromo-2-nitro-
• 2-Nitro-5-bromopyridine

5-Bromo-2-nitropyridine

CAS: 39856-50-3

Formula: C₅H₃BrN₂O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 202.9935

Ref: IN-DA00347V

5-Bromo-2-nitropyridine

CAS: 39856-50-3

Formula: C₅H₃BrN₂O₂

Molecular weight: 203.00

Ref: 7W-GK1819

5-Bromo-2-nitropyridine

CAS: 39856-50-3

5-Bromo-2-nitropyridine

Formula: C₅H₃BrN₂O₂

Purity: ≥95%

Color and Shape: pale yellow solid

Molecular weight: 202.99352g/mol

Ref: 54-OR4485

Risdiplam Impurity 8

CAS: 39856-50-3

Formula: C₅H₃BrN₂O₂

Molecular weight: 203.00

Ref: 4Z-R-144010

5-Bromo-2-nitropyridine

CAS: 39856-50-3

Formula: C₅H₃BrN₂O₂

Purity: >98.0%(GC)

Color and Shape: White to Light gray to Green powder to crystal

Molecular weight: 203.00

Ref: 3B-B2766

5-Bromo-2-nitropyridine

CAS: 39856-50-3

Formula: C₅H₃BrN₂O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 202.995

Ref: 10-F043668

5-Bromo-2-nitropyridine

Controlled Product

CAS: 39856-50-3

Applications 5-Bromo-2-nitropyridine is employed as a reagent in the synthesis of novel benzinidazoles, potent inhibitors of TIE-2 and VEGFR-2 Tyrosine (T899975) kinase receptors.
References Hasegawa, M., et al.: J. Med. Chem., 50, 4453 (2007); Okaniwa, M., et al.: J. Med. Chem., 55, 3452 (2012)

Formula: C₅H₃BrN₂O₂

Color and Shape: Neat

Molecular weight: 202.99

Ref: TR-B686180

5-Bromo-2-nitropyridine

CAS: 39856-50-3

Formula: C₅H₃BrN₂O₂

Molecular weight: 203

Ref: ST-EA-CP-P65099

5-Bromo-2-nitropyridine

CAS: 39856-50-3

5-Bromo-2-nitropyridine is a hydrogen bond donor. It is an organic molecule with the chemical formula C5H5BrN3. The compound has been used in the synthesis of other molecules, such as nicotinic acetylcholine and mitochondrial membrane potential inhibitors. 5-Bromo-2-nitropyridine is also a good candidate for cancer treatment due to its ability to inhibit cell cycle progression at G2/M phase. 5-Bromo-2-nitropyridine can be synthesized by reacting 2,4,6-trinitrobenzenesulfonic acid with bromine and potassium carbonate in a reaction vessel at 200 °C for about 30 minutes.

Formula: C₅H₃BrN₂O₂

Color and Shape: Powder

Molecular weight: 202.99 g/mol

Ref: 3D-FB55265