CAS 39860-99-6

Pipotiazine

Description:

Pipotiazine is an antipsychotic medication primarily used in the treatment of schizophrenia and other psychotic disorders. It belongs to the thienobenzodiazepine class of compounds and exhibits both antipsychotic and sedative properties. The chemical structure of pipotiazine includes a thienobenzodiazepine core, which contributes to its pharmacological effects. It functions mainly as a dopamine receptor antagonist, particularly targeting D2 receptors, which helps in alleviating symptoms of psychosis. Additionally, pipotiazine may have effects on serotonin receptors, contributing to its overall therapeutic profile. The substance is typically administered in the form of its hydrochloride salt, enhancing its solubility and bioavailability. Common side effects may include sedation, weight gain, and extrapyramidal symptoms, which are typical of many antipsychotic medications. Due to its pharmacological properties, pipotiazine is often prescribed in a controlled manner, with careful monitoring for potential adverse effects. As with all medications, it is essential for patients to consult healthcare professionals for personalized advice and management.

Formula: C₂₄H₃₃N₃O₃S₂

InChI: InChI=1S/C24H33N3O3S2/c1-25(2)32(29,30)20-8-9-24-22(18-20)27(21-6-3-4-7-23(21)31-24)14-5-13-26-15-10-19(11-16-26)12-17-28/h3-4,6-9,18-19,28H,5,10-17H2,1-2H3

InChI key: InChIKey=JOMHSQGEWSNUKU-UHFFFAOYSA-N

SMILES: C(CCN1CCC(CCO)CC1)N2C=3C(SC=4C2=CC=CC4)=CC=C(S(N(C)C)(=O)=O)C3

Synonyms:

• 10-[3-[4-(2-Hydroxyethyl)-1-piperidinyl]propyl]-N,N-dimethyl-10H-phenothiazine-2-sulfonamide
• 19366Rp
• Lonseren
• Piportil
• Pipothiazine
• Pipotiazin
• Pipotiazina
• Pipotiazine
• Rp 19366
• 10H-Phenothiazine-2-sulfonamide, 10-[3-[4-(2-hydroxyethyl)-1-piperidinyl]propyl]-N,N-dimethyl-
• 10-{3-[4-(2-hydroxyethyl)piperidin-1-yl]propyl}-N,N-dimethyl-10H-phenothiazine-2-sulfonamide

Pipotiazine

CAS: 39860-99-6

Formula: C₂₄H₃₃N₃O₃S₂

Molecular weight: 475.68

Ref: 4Z-P-289001

Pipotiazine

CAS: 39860-99-6

Pipotiazine treats chronic schizophrenia with less sedation, low hypotension risk, but high extrapyramidal side effects.

Formula: C₂₄H₃₃N₃O₃S₂

Color and Shape: Solid

Molecular weight: 475.67

Ref: TM-T34072