CAS 39929-79-8

7-Deazaxanthine

Description:

7-Deazaxanthine is a purine derivative and a structural analog of xanthine, characterized by the absence of a nitrogen atom at the 7-position of the xanthine molecule. This modification influences its biochemical properties and interactions. It is typically a white to off-white solid that is soluble in polar solvents, such as water and dimethyl sulfoxide (DMSO), but may have limited solubility in non-polar solvents. The compound is of interest in biochemical research, particularly in studies related to nucleic acid metabolism and enzyme inhibition. Its structural similarity to xanthine allows it to interact with various enzymes, potentially serving as a substrate or inhibitor. Additionally, 7-deazaxanthine may exhibit antioxidant properties, contributing to its potential applications in pharmacology and biochemistry. As with many chemical substances, handling should be conducted with care, following appropriate safety protocols to mitigate any risks associated with exposure.

Formula: C₆H₅N₃O₂

InChI: InChI=1S/C6H5N3O2/c10-5-3-1-2-7-4(3)8-6(11)9-5/h1-2H,(H3,7,8,9,10,11)

InChI key: InChIKey=HASUWNAFLUMMFI-UHFFFAOYSA-N

SMILES: O=C1C2=C(NC(=O)N1)NC=C2

Synonyms:

• 1,7-Dihydro-pyrrolo[2,3-d]pyrimidine-2,4-dione
• 1,7-Dihydropyrrolo[2,3-d]pyrimidine-2,4-dione
• 1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione
• 7-Deazaxanthine
• 7H-Pyrrolo[2,3-d]pyrimidine-2,4-diol

7H-Pyrrolo[2,3-d]pyrimidine-2,4-diol

CAS: 39929-79-8

Formula: C₆H₅N₃O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 151.1228

Ref: IN-DA00BYHT

7H-Pyrrolo[2,3-d]pyrimidine-2,4-diol

CAS: 39929-79-8

7H-Pyrrolo[2,3-d]pyrimidine-2,4-diol

Purity: 95

Color and Shape: Pale Brown To Brown Powder

Molecular weight: 151.12g/mol

Ref: 54-OR3109

7-Deazaxanthine

CAS: 39929-79-8

7-Deazaxanthine (7DX) is an inhibitor of thymidine phosphorylase (TPase) and reduces TPase activity in a concentration-dependent manner, with an IC50 value of 40 μM. Additionally, 7-Deazaxanthine exhibits significant anti-angiogenic properties.

Formula: C₆H₅N₃O₂

Color and Shape: Solid

Molecular weight: 151.12

Ref: TM-T203650

Tofacitinib Impurity 46

CAS: 39929-79-8

Formula: C₆H₅N₃O₂

Molecular weight: 151.038

Ref: 4Z-T-117118

2,4-Dihydroxypyrrolo[2,3-d]pyrimidine

CAS: 39929-79-8

Applications 2,4-Dihydroxypyrrolo[2,3-d]pyrimidine (cas# 39929-79-8) is a compound useful in organic synthesis.

Formula: C₆H₅N₃O₂

Color and Shape: Neat

Molecular weight: 151.12

Ref: TR-D454675

7-Deazaxanthine

CAS: 39929-79-8

7-Deazaxanthine is a purine derivative that has been shown to have antiangiogenic properties. It inhibits the growth of cancer cells by inhibiting the synthesis of vascular endothelial growth factor (VEGF), which is a potent angiogenic factor. 7-Deazaxanthine also binds to the VEGF receptor, preventing it from binding to VEGF. The x-ray crystal structures and kinetic data for 7-deazaadenosine suggest that this compound may be an inhibitor of hydrogen bonding interactions between amino acids in protein molecules, leading to its antiangiogenic activity. 7-Deazaxanthine does not prevent the activation of tyrosine kinases or phosphatases. In addition, this compound has been shown to inhibit the proliferation of breast cancer cells in culture and in vivo studies using mouse models. This drug also has glycosidic bond, which can result in a variety of chemical structures due to different types of glycos

Formula: C₆H₅N₃O₂

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 151.12 g/mol

Ref: 3D-FD11329

1,7-Dihydro-pyrrolo[2,3-d]pyrimidine-2,4-dione

CAS: 39929-79-8

Formula: C₆H₅N₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 151.125

Ref: 10-F049593

Tofacitinib Impurity 178

CAS: 39929-79-8

Formula: C₆H₅N₃O₂

Molecular weight: 151.038

Ref: ST-EA-CP-T23160