CAS 3993-78-0

2-AMINO-4-CHLOROPYRIMIDINE

Description:

2-Amino-4-chloropyrimidine is an organic compound characterized by its pyrimidine ring structure, which includes an amino group (-NH2) and a chlorine atom (Cl) at the 2 and 4 positions, respectively. This compound is typically a white to off-white crystalline solid and is soluble in polar solvents such as water and alcohols, reflecting its polar functional groups. It has applications in pharmaceuticals and agrochemicals, often serving as an intermediate in the synthesis of various biologically active compounds. The presence of the amino and chloro substituents contributes to its reactivity, allowing for further chemical modifications. Additionally, 2-amino-4-chloropyrimidine can participate in various reactions, including nucleophilic substitutions and coupling reactions, making it a valuable building block in organic synthesis. Its molecular structure and properties make it of interest in medicinal chemistry, particularly in the development of antiviral and anticancer agents. Safety data should be consulted for handling and storage, as with any chemical substance.

Formula: C₄H₄ClN₃

InChI: InChI=1/C4H4ClN3/c5-3-1-2-7-4(6)8-3/h1-2H,(H2,6,7,8)

SMILES: c1c[nH]c(=N)nc1Cl

Synonyms:

• 4-Chloropyrimidin-2-Amine

2-Amino-4-chloropyrimidine, 98%

CAS: 3993-78-0

2-Amino-4-chloropyrimidine is a substrate used in a palladium-catalyzed cyanation with zinc(II) cyanide. It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff fields. This Thermo Scientific Chemicals brand product was originally part

Formula: C₄H₄ClN₃

Purity: 98%

Molecular weight: 129.55

Ref: 02-H55007

2-Pyrimidinamine, 4-chloro-

CAS: 3993-78-0

Formula: C₄H₄ClN₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 129.5477

Ref: IN-DA00I7U2

2-Amino-4-chloropyrimidine

CAS: 3993-78-0

Formula: C₄H₄ClN₃

Molecular weight: 129.55

Ref: 7W-GN0909

2-Amino-4-chloropyrimidine

CAS: 3993-78-0

2-Amino-4-chloropyrimidine

Formula: C₄H₄ClN₃

Purity: 98%

Color and Shape: faint yellow crystalline solid

Molecular weight: 129.55g/mol

Ref: 54-OR3722

4-Chloropyrimidin-2-amine

CAS: 3993-78-0

Formula: C₄H₄ClN₃

Purity: >95.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 129.55

Ref: 3B-A2150

2-Amino-4-chloropyrimidine

CAS: 3993-78-0

2-Amino-4-chloropyrimidine is an amido compound that is used to treat infectious diseases. It is a potent inhibitor of the enzyme topoisomerase II, which is involved in DNA replication and transcription. This drug has shown cytotoxic activity against du145 cells, an immortalized prostate cancer cell line. 2-Amino-4-chloropyrimidine has also been shown to be effective against MDA-MB-231 cells and thp1 cells, which are human breast cancer cell lines. 2-Amino-4-chloropyrimidine binds to the active site of topoisomerase II, preventing the enzyme from binding with the two ends of DNA and causing DNA breakage. The drug has also been shown to inhibit the growth of cervical cancer cells by binding with amine groups on proteins found on these cells.

Formula: C₄H₄ClN₃

Purity: 80

Color and Shape: White Powder

Molecular weight: 129.55 g/mol

Ref: 3D-FA11523

2-Amino-4-chloropyrimidine

CAS: 3993-78-0

Formula: C₄H₄ClN₃

Purity: 98%

Color and Shape: Solid, Chunks or Crystalline Powder

Molecular weight: 129.55

Ref: 10-F036341